Synthesis of Various Water-Soluble C60 Derivatives and Their Superoxide-Quenching Activity

K. Okuda, T. Hirota, M. Hirobe, T. Nagano, M. Mochizuki, T. Mashino
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引用次数: 36

Abstract

Abstract In order to examine the utility of fullerene as a medicinal application, we evaluated the reaction between fullerene derivatives and active oxygen species in vitro. This paper describes the synthesis of various water-soluble C60 derivatives (cationic and anionic) and evaluation of their superoxide (O2 −) quenching activity. Cationic C60 derivatives showed fairly high efficiency.
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各种水溶性C60衍生物的合成及其超氧猝灭活性
摘要为了研究富勒烯的药用价值,我们在体外研究了富勒烯衍生物与活性氧的反应。本文介绍了各种水溶性C60衍生物(阳离子和阴离子)的合成及其超氧化物(O2−)猝灭活性的评价。阳离子C60衍生物表现出相当高的效率。
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TETHER-LINKED [60]FULLERENE-DONOR DYADS EVIDENCES ABOUT CARBYNE FORMATION TOGETHER WITH OTHER CARBONACEOUS MATERIAL BY THERMAL DECOMPOSITION OF DIIODOACETYLENE PHASE DIAGRAM OF K-C60 SYSTEM SOLUBILITY CORRELATION OF [60]FULLERENE IN DIFFERENT SOLVENTS AN FT-ICR STUDY ON LASER ABLATION OF GRAPHITE AND CARBON BLACK TARGETS: COSMOCHEMICAL IMPLICATIONS
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