Multiple urolithiases in pediatric acute lymphoblastic leukemia

Ayumi Fujishiro, Ryosuke Matsuno, Taichi Omachi, Takashi Yamazoe, M. Okano, K. Kaneko
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Abstract

Current study is a case report of a 5-year-old patient with T-cell acute lymphoblastic leukemia (ALL) and multiple urolithiasis. Complex factors, including glucocorticoid-induced hypercalciuria, fluid restriction for the syndrome of inappropriate secretion of antidiuretic hormone, and long-term bed rest, predispose children with ALL to develop urolithiasis. To prevent urinary urolithiasis formation, urinary calcium excretion should be monitored during chemotherapy and when administering glucocorticoids.
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小儿急性淋巴细胞白血病多发尿石症
本研究报告一例5岁的t细胞急性淋巴细胞白血病(ALL)合并多发性尿石症患者。糖皮质激素诱导的高钙尿症、因抗利尿激素分泌不当引起的流质限制以及长期卧床休息等复杂因素使ALL患儿易患尿石症。为了防止尿石症的形成,在化疗期间和使用糖皮质激素时应监测尿钙排泄。
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