The Cognitive and Language Profile of Dementia with Lewy Bodies

J. Macoir
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Abstract

Dementia with Lewy bodies (DLB) is a major neurocognitive disorder (MNCD) that is primarily characterized by motor, cognitive, and behavioral symptoms. Although not dominant in the clinical portrait of DLB, impairments affecting language processing have been reported. It is sometimes challenging to differentiate DLB from Alzheimer’s disease and dementia associated with Parkinson’s disease in clinical practice. Therefore, a better comprehension of the typical clinical presentation of DLB may be useful to ease the medical diagnosis. In this article, current data on cognitive and language disorders in DLB are reported, with special attention paid to their primary or secondary functional origin. The main elements that should be considered for the neuropsychological and speech-language assessment of individuals with possible or proven DLB are also highlighted. Additional studies are needed, especially for language impairment, to obtain a more accurate portrait of the clinical presentation of DLB and characterize its progression.
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路易体痴呆患者的认知和语言特征
路易体痴呆(DLB)是一种主要的神经认知障碍(MNCD),主要表现为运动、认知和行为症状。虽然在DLB的临床表现中不占主导地位,但影响语言处理的损伤已被报道。在临床实践中,有时很难将DLB与阿尔茨海默病和帕金森病相关的痴呆区分开来。因此,更好地理解DLB的典型临床表现可能有助于简化医学诊断。本文报道了DLB中认知和语言障碍的最新数据,并特别关注其原发性或继发性功能起源。本文还强调了对可能或已证实的DLB患者进行神经心理学和言语语言评估时应考虑的主要因素。需要进一步的研究,特别是对语言障碍的研究,以获得更准确的DLB临床表现和表征其进展。
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