Nanocomposite Polymer Scaffolds Responding under External Stimuli for Drug Delivery and Tissue Engineering Applications

A. Hébraud, G. Schlatter, J. Goetz, S. Harlepp, S. Bégin-Colin, D. Mertz
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Abstract

The blossoming development of nanomaterials and polymer science has opened the way toward new biocompatible scaffolds responding remotely to external stimuli (magnetic field, light, electric field). Such smart scaffolds are envisioned as new implantable tissues displaying multiple therapeutic and imaging functionalities. They hold great promises to achieve a controlled delivery of therapeutics for various diseases, or to ensure a stimuli-induced cellular response for bone, cardiac, or muscle tissue engineering.
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纳米复合聚合物支架在外部刺激下的药物传递和组织工程应用
纳米材料和聚合物科学的蓬勃发展为新型生物相容性支架开辟了道路,这些支架可以远程响应外部刺激(磁场、光、电场)。这种智能支架被设想为具有多种治疗和成像功能的新型植入式组织。它们有望实现各种疾病治疗的受控递送,或确保骨、心脏或肌肉组织工程的刺激诱导细胞反应。
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