The Changing Face of the Cornea in a Case of Juvenile Glaucoma and Subclinical Keratoconus.

IF 4.1 3区 材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY Mrs Bulletin Pub Date : 2024-11-01 Epub Date: 2022-04-06 DOI:10.1055/a-1819-1412
Ahmad K Khalil
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Abstract

We report on a 23-year-old man who presented with bilateral subclinical keratoconus and juvenile glaucoma (JG). With intraocular pressures (IOPs) of 30 and 28 mmHg, both eyes were consecutively operated by adjusted trabeculotomy, leading to a remarkable decrease in IOP to well below the mean for this surgery in JG. Meanwhile, most keratoconus indices clearly progressed in the first 5 months postoperatively, with increases in corneal hysteresis, associated with a remarkable drop in the corneal resistance factor. During the following years, IOP remained low, and all changes (except the increase in corneal hysteresis) reverted to near preoperative levels through the follow-up course of 5 years. This report complements a few existing reports that show the coincidence of keratoconus and JG, and, more importantly, documents a novel pattern of remarkable and prolonged corneal changes following surgical lowering of IOP in eyes with these changes. Postoperative biomechanical disturbances in the cornea and possibly limbus are proposed in cases of JG and subclinical keratoconus.

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青少年青光眼和亚临床角膜炎病例中角膜的变化。
我们报告了一名 23 岁男子的病例,他患有双侧亚临床角膜病和幼年青光眼(JG)。在眼压(IOP)分别为 30 和 28 mmHg 的情况下,他的双眼连续接受了调整型小梁切开术,结果眼压显著下降,远低于 JG 手术的平均值。与此同时,大多数角膜病指标在术后头 5 个月明显恶化,角膜滞后增加,角膜阻力因子显著下降。在随后的几年中,眼压一直很低,所有的变化(除了角膜滞后的增加)都在 5 年的随访过程中恢复到接近术前的水平。这份报告补充了现有的几份关于角膜炎和 JG 并发症的报告,更重要的是,它记录了一种新的模式,即在手术降低眼压后,角膜会发生显著而持久的变化。在 JG 和亚临床角膜炎病例中,角膜和角膜缘可能存在术后生物力学紊乱。
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来源期刊
Mrs Bulletin
Mrs Bulletin 工程技术-材料科学:综合
CiteScore
7.40
自引率
2.00%
发文量
193
审稿时长
4-8 weeks
期刊介绍: MRS Bulletin is one of the most widely recognized and highly respected publications in advanced materials research. Each month, the Bulletin provides a comprehensive overview of a specific materials theme, along with industry and policy developments, and MRS and materials-community news and events. Written by leading experts, the overview articles are useful references for specialists, but are also presented at a level understandable to a broad scientific audience.
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