W. M. Giufrida, R. Favareto, Vladimir F. Giufrida, Willyan M. Cabral, M. Meireles, L. Cardozo-Filho, M. Corazza
{"title":"High-Pressure Vapor-Liquid Equilibrium Data for Ternary Systems CO2+ Organic Solvent + Curcumin","authors":"W. M. Giufrida, R. Favareto, Vladimir F. Giufrida, Willyan M. Cabral, M. Meireles, L. Cardozo-Filho, M. Corazza","doi":"10.2174/1874123101004010003","DOIUrl":null,"url":null,"abstract":"In the present work phase equilibrium data for the ternary systems CO2 + ethanol + curcumin and CO2 + ethyl acetate + curcumin, at different concentrations of curcumin in the organic solvent (0.01 g cm -3 , 0.005 g cm -3 for ethanol and 0.01 g cm -3 , 0.0025 g cm -3 for ethyl acetate) are reported. The static synthetic method, using a variable-volume view cell was employed for obtaining the experimental data in the temperature range of (303 to 333) K and pressures up to 11 MPa. Vapor-liquid phase transitions were observed as bubble and dew points for the overall compositions investigated. The phase equilibria of the ternary systems were fitted to the Peng-Robinson equation of state (PR-EoS) using only binary system information. Experimental data together with modeling results may constitute relevant information for the precipitation of curcumin using the supercritical antisolvent process.","PeriodicalId":22933,"journal":{"name":"The Open Chemical Engineering Journal","volume":"69 1","pages":"3-10"},"PeriodicalIF":0.0000,"publicationDate":"2014-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"11","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Open Chemical Engineering Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1874123101004010003","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 11
Abstract
In the present work phase equilibrium data for the ternary systems CO2 + ethanol + curcumin and CO2 + ethyl acetate + curcumin, at different concentrations of curcumin in the organic solvent (0.01 g cm -3 , 0.005 g cm -3 for ethanol and 0.01 g cm -3 , 0.0025 g cm -3 for ethyl acetate) are reported. The static synthetic method, using a variable-volume view cell was employed for obtaining the experimental data in the temperature range of (303 to 333) K and pressures up to 11 MPa. Vapor-liquid phase transitions were observed as bubble and dew points for the overall compositions investigated. The phase equilibria of the ternary systems were fitted to the Peng-Robinson equation of state (PR-EoS) using only binary system information. Experimental data together with modeling results may constitute relevant information for the precipitation of curcumin using the supercritical antisolvent process.
本文报道了CO2 +乙醇+姜黄素和CO2 +乙酸乙酯+姜黄素三元体系在不同浓度的有机溶剂(乙醇为0.01 g cm -3、0.005 g cm -3,乙酸乙酯为0.01 g cm -3、0.0025 g cm -3)下的相平衡数据。采用静态合成方法,在温度为(303 ~ 333)K,压力为11 MPa的条件下,采用变体积观察池获得实验数据。汽液相变以气泡和露点的形式被观察到。仅利用二元系统的信息,将三元体系的相平衡拟合到Peng-Robinson状态方程(PR-EoS)。实验数据和模拟结果可为超临界反溶剂法沉淀姜黄素提供相关信息。