{"title":"Micro bubble fluidics by EWOD and ultrasonic excitation for micro bubble tweezers","authors":"S. Chung, Yuejun Zhao, U. Yi, S. Cho","doi":"10.1109/MEMSYS.2007.4433051","DOIUrl":null,"url":null,"abstract":"Recently, we envisioned so called micro bubble tweezers where EWOD (electrowetting-on-dielectric) actuated bubbles can manipulate micro objects such as biological cells by pushing or pulling them. Besides, oscillating (shrinking and expanding) bubbles in the presence of ultrasonic wave act as a to deliver drugs and molecules into the cells. In this paper, as a great stride in our quest for micro bubble tweezers, we present (1) full realization of two critical bubble operations (generating of bubbles in an on-chip and on-demand manner and splitting of single bubbles) and (2) two possible applications of mobile bubbles oscillating under acoustic excitation (a mobile vortex generator and micro particle carrier).","PeriodicalId":6388,"journal":{"name":"2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS)","volume":"66 6 1","pages":"31-34"},"PeriodicalIF":0.0000,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"16","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/MEMSYS.2007.4433051","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 16
Abstract
Recently, we envisioned so called micro bubble tweezers where EWOD (electrowetting-on-dielectric) actuated bubbles can manipulate micro objects such as biological cells by pushing or pulling them. Besides, oscillating (shrinking and expanding) bubbles in the presence of ultrasonic wave act as a to deliver drugs and molecules into the cells. In this paper, as a great stride in our quest for micro bubble tweezers, we present (1) full realization of two critical bubble operations (generating of bubbles in an on-chip and on-demand manner and splitting of single bubbles) and (2) two possible applications of mobile bubbles oscillating under acoustic excitation (a mobile vortex generator and micro particle carrier).
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