{"title":"The Nucleotide Sequence of the tRNA{ie} from the Archaebacterium Thermoplasma acidophilum","authors":"Michael W. Kilpatrick, Richard T. Walker","doi":"10.1016/S0721-9571(82)80056-2","DOIUrl":null,"url":null,"abstract":"<div><p>The nucleotide sequence of <em>Thermoplasma acidophilum</em> tRNA{ie} has been shown to be: pGCCGGGGs<sup>4</sup>UGGCUCANCUGGAGGAGCm<sub>2</sub><sup>2</sup>GCCGGAC<sub>m</sub> UCAUt<sup>6</sup>AAUCCGGAG-GUCUCGGGψψC<sub>m</sub>GAUCCCCGAUCCCGGCACCA<sub>oH</sub>. The tRNA contains eight modified nucleosides including the sequence ψψC<sub>m</sub> (54–56) which has been proposed as a unique feature of archaebacterial tRNAs. One modification is unknown but it is likely to be typically archaebacterial (N-15). Of the remaining four, one (s<sup>4</sup>U-8) is a typical eubac-terial modification and one (m<sub>2</sub><sup>2</sup>G-26) is a typical eukaryotic modification. The sequence shows little homology with any other published tRNA but shows almost 90% homology with the ancestral quasi-species sequence deduced by <em>Eigen</em> and <em>Winter-Oswatitsch</em> (1981).</p></div>","PeriodicalId":101290,"journal":{"name":"Zentralblatt für Bakteriologie Mikrobiologie und Hygiene: I. Abt. Originale C: Allgemeine, angewandte und ?kologische Mikrobiologie","volume":"3 1","pages":"Pages 79-89"},"PeriodicalIF":0.0000,"publicationDate":"1982-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0721-9571(82)80056-2","citationCount":"36","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zentralblatt für Bakteriologie Mikrobiologie und Hygiene: I. Abt. Originale C: Allgemeine, angewandte und ?kologische Mikrobiologie","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0721957182800562","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 36
Abstract
The nucleotide sequence of Thermoplasma acidophilum tRNA{ie} has been shown to be: pGCCGGGGs4UGGCUCANCUGGAGGAGCm22GCCGGACm UCAUt6AAUCCGGAG-GUCUCGGGψψCmGAUCCCCGAUCCCGGCACCAoH. The tRNA contains eight modified nucleosides including the sequence ψψCm (54–56) which has been proposed as a unique feature of archaebacterial tRNAs. One modification is unknown but it is likely to be typically archaebacterial (N-15). Of the remaining four, one (s4U-8) is a typical eubac-terial modification and one (m22G-26) is a typical eukaryotic modification. The sequence shows little homology with any other published tRNA but shows almost 90% homology with the ancestral quasi-species sequence deduced by Eigen and Winter-Oswatitsch (1981).