Using Demarcation Criteria as a Tool for Evaluating Controversial Case of andldquo;Water Memoryandrdquo;

E. Rezazadeh, Iman Rad
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Abstract

Definition of biological activity, which results in a biological property, is still inspired by conventional Fischer’s ‘lock- and-key’ model. This model explains how the correctly sized key (ligand) should fits into the keyhole (receptor) in an analogical manner. During Electromagnetic Information Transfer (EMIT), property of original molecule delivers either to water or target biological entity. In cases that water receives a property via EMIT, it imitates the original agonist, while no longer has the molecule inside it. The recent concept is known as “Water Memory (WM)”. EMIT and WM, challenge the currently admired scientific paradigm (lock-and-key model), which addresses the necessity of structural conformity of interacting molecules. Considering the fact that replicability of EMIT and WM related empirical studies are not always confirmed, these propositions are mostly labelled as “pseudoscience”. To evaluate the authenticity of labelling EMIT and WM as pseudoscience, we debated the scientific accuracy of EMIT phenomenon with demarcation criteria. Either of the agreement or disagreements of the proposed propositions, which explain EMIT and WM, evaluated and scored by Delphi analysis. Results of our Delphi analysis confirm that some of the propositions that explain EMIT or WM, splendidly pass the prerequisites of demarcation criteria. Therefore, labelling the aforementioned propositions as pseudoscience is content to perfunctory generalization, which needs to be revised. Further investigation of the propositions that merited demarcation criteria, helps to establish a scientific framework that explains ground-breaking aspects of EMIT and WM phenomena.
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以划界标准为工具评价水资源记忆争议案件
生物活性的定义,即生物特性的产生,仍然受到传统费舍尔的“锁与钥匙”模型的启发。这个模型以类比的方式解释了正确大小的钥匙(配体)应该如何适应钥匙孔(受体)。在电磁信息传递(EMIT)过程中,原始分子的特性传递给水或目标生物实体。如果水通过EMIT获得一种特性,它会模仿原来的激动剂,而不再有分子在里面。最近的概念被称为“水记忆(WM)”。EMIT和WM挑战了目前备受推崇的科学范式(锁与钥匙模型),该模型解决了相互作用分子结构一致性的必要性。考虑到EMIT和WM相关实证研究的可重复性并不总是得到证实,这些主张大多被贴上“伪科学”的标签。为了评估将EMIT和WM标记为伪科学的真实性,我们用划分标准讨论了EMIT现象的科学准确性。提出的命题的一致或不一致,这解释了EMIT和WM,通过德尔菲分析进行评估和评分。我们的德尔菲分析结果证实,一些解释EMIT或WM的命题,很好地通过了划分标准的先决条件。因此,将上述命题贴上伪科学的标签是满足于敷衍的概括,需要修正。对符合划界标准的命题的进一步调查,有助于建立一个科学框架,解释EMIT和WM现象的突破性方面。
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