Pub Date : 2021-01-01DOI: 10.35248/2161-0398.21.11.294
E. Salman, Amenah Kadhim Murad
The adverse health effects of exposure to radon are caused primarily by damage due to alpha-particles. The possible effects will depend on exposure level. The main danger from high radon exposure is an increased risk of lung cancer. Radon as a noble gas is rapidly exhaled after being breathed in; however, radon progeny combine with other molecules in the air and with particles of dust, aerosols or smoke, and readily deposit in the airways of the lung. While lodging there, the progeny emit ionizing radiation in the form of alpha particles, which can damage the cells lining the airways. Experiments have confirmed that ionizing radiation affecting bronchial epithelial cells could cause cancer.
{"title":"Radioactivity: Radon Gas, its Properties and the Risks of Increasing its Concentration","authors":"E. Salman, Amenah Kadhim Murad","doi":"10.35248/2161-0398.21.11.294","DOIUrl":"https://doi.org/10.35248/2161-0398.21.11.294","url":null,"abstract":"The adverse health effects of exposure to radon are caused primarily by damage due to alpha-particles. The possible effects will depend on exposure level. The main danger from high radon exposure is an increased risk of lung cancer. Radon as a noble gas is rapidly exhaled after being breathed in; however, radon progeny combine with other molecules in the air and with particles of dust, aerosols or smoke, and readily deposit in the airways of the lung. While lodging there, the progeny emit ionizing radiation in the form of alpha particles, which can damage the cells lining the airways. Experiments have confirmed that ionizing radiation affecting bronchial epithelial cells could cause cancer.","PeriodicalId":94103,"journal":{"name":"Journal of physical chemistry & biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87860627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.35248/2161-0398.21.11.302
C. Ribeiro
{"title":"Biomaterials in the Field of Dental Implantation","authors":"C. Ribeiro","doi":"10.35248/2161-0398.21.11.302","DOIUrl":"https://doi.org/10.35248/2161-0398.21.11.302","url":null,"abstract":"","PeriodicalId":94103,"journal":{"name":"Journal of physical chemistry & biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82617954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.35248/2161-0398.21.11.296
Bello Warren
{"title":"Antioxidant and its Adverse Effects","authors":"Bello Warren","doi":"10.35248/2161-0398.21.11.296","DOIUrl":"https://doi.org/10.35248/2161-0398.21.11.296","url":null,"abstract":"","PeriodicalId":94103,"journal":{"name":"Journal of physical chemistry & biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79756084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.35248/2161-0398.21.11.295
E. Rezazadeh, Iman Rad
Definition of biological activity, which results in a biological property, is still inspired by conventional Fischer’s ‘lock- and-key’ model. This model explains how the correctly sized key (ligand) should fits into the keyhole (receptor) in an analogical manner. During Electromagnetic Information Transfer (EMIT), property of original molecule delivers either to water or target biological entity. In cases that water receives a property via EMIT, it imitates the original agonist, while no longer has the molecule inside it. The recent concept is known as “Water Memory (WM)”. EMIT and WM, challenge the currently admired scientific paradigm (lock-and-key model), which addresses the necessity of structural conformity of interacting molecules. Considering the fact that replicability of EMIT and WM related empirical studies are not always confirmed, these propositions are mostly labelled as “pseudoscience”. To evaluate the authenticity of labelling EMIT and WM as pseudoscience, we debated the scientific accuracy of EMIT phenomenon with demarcation criteria. Either of the agreement or disagreements of the proposed propositions, which explain EMIT and WM, evaluated and scored by Delphi analysis. Results of our Delphi analysis confirm that some of the propositions that explain EMIT or WM, splendidly pass the prerequisites of demarcation criteria. Therefore, labelling the aforementioned propositions as pseudoscience is content to perfunctory generalization, which needs to be revised. Further investigation of the propositions that merited demarcation criteria, helps to establish a scientific framework that explains ground-breaking aspects of EMIT and WM phenomena.
{"title":"Using Demarcation Criteria as a Tool for Evaluating Controversial Case of andldquo;Water Memoryandrdquo;","authors":"E. Rezazadeh, Iman Rad","doi":"10.35248/2161-0398.21.11.295","DOIUrl":"https://doi.org/10.35248/2161-0398.21.11.295","url":null,"abstract":"Definition of biological activity, which results in a biological property, is still inspired by conventional Fischer’s ‘lock- and-key’ model. This model explains how the correctly sized key (ligand) should fits into the keyhole (receptor) in an analogical manner. During Electromagnetic Information Transfer (EMIT), property of original molecule delivers either to water or target biological entity. In cases that water receives a property via EMIT, it imitates the original agonist, while no longer has the molecule inside it. The recent concept is known as “Water Memory (WM)”. EMIT and WM, challenge the currently admired scientific paradigm (lock-and-key model), which addresses the necessity of structural conformity of interacting molecules. Considering the fact that replicability of EMIT and WM related empirical studies are not always confirmed, these propositions are mostly labelled as “pseudoscience”. To evaluate the authenticity of labelling EMIT and WM as pseudoscience, we debated the scientific accuracy of EMIT phenomenon with demarcation criteria. Either of the agreement or disagreements of the proposed propositions, which explain EMIT and WM, evaluated and scored by Delphi analysis. Results of our Delphi analysis confirm that some of the propositions that explain EMIT or WM, splendidly pass the prerequisites of demarcation criteria. Therefore, labelling the aforementioned propositions as pseudoscience is content to perfunctory generalization, which needs to be revised. Further investigation of the propositions that merited demarcation criteria, helps to establish a scientific framework that explains ground-breaking aspects of EMIT and WM phenomena.","PeriodicalId":94103,"journal":{"name":"Journal of physical chemistry & biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90169397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.35248/2161-0401.20.10.282
F. Alotaibi
Appropriately administered antibiotic prophylaxis reduces the incidence of surgical wound infection. Prophylaxis is uniformly recommended for all clean-contaminated, contaminated and dirty procedures. It is considered optional for most clean procedures, although it may be indicated for certain patients and clean procedures that fulfill specific risk criteria.
{"title":"The Practice of Preoperative Antibiotic Prophylaxis and the Adherence to ASHP Guideline in Different Hospitals in Riyadh","authors":"F. Alotaibi","doi":"10.35248/2161-0401.20.10.282","DOIUrl":"https://doi.org/10.35248/2161-0401.20.10.282","url":null,"abstract":"Appropriately administered antibiotic prophylaxis reduces the incidence of surgical wound infection. Prophylaxis is uniformly recommended for all clean-contaminated, contaminated and dirty procedures. It is considered optional for most clean procedures, although it may be indicated for certain patients and clean procedures that fulfill specific risk criteria.","PeriodicalId":94103,"journal":{"name":"Journal of physical chemistry & biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90022076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.4172/2161-0398.1000278
R. Mehrnejad
Biological shielding of nuclear reactor is an important interest and diminishing the intricacy and cost of theseinstallations is important interest. In this paper, we used Datolite and Galena minerals and boron carbide for nuclear reactor shielding aim. Datolite and Galena minerals that exist in many parts of world were used in the concrete mix design. Boron carbide is an important material for neutron absorption processes. The cross section in matter and neutron capture is utilizable causes to explain neutron shielding characteristics of samples. Neutron cross section simulations of samples have done by using a source of 14.1 MeV reactor neutrons. Cross section and number of captured neutrons of each sample were estimated by using Geant4 Monte Carlo code. As a result, growing boron carbide concentration can raise cross section value of Datolite and galena.
{"title":"Improving Neutron Shielding Capacities of Datolite and Galena by Boron Carbide Additive for Nuclear Reactor Biological Shielding","authors":"R. Mehrnejad","doi":"10.4172/2161-0398.1000278","DOIUrl":"https://doi.org/10.4172/2161-0398.1000278","url":null,"abstract":"Biological shielding of nuclear reactor is an important interest and diminishing the intricacy and cost of theseinstallations is important interest. In this paper, we used Datolite and Galena minerals and boron carbide for nuclear reactor shielding aim. Datolite and Galena minerals that exist in many parts of world were used in the concrete mix design. Boron carbide is an important material for neutron absorption processes. The cross section in matter and neutron capture is utilizable causes to explain neutron shielding characteristics of samples. Neutron cross section simulations of samples have done by using a source of 14.1 MeV reactor neutrons. Cross section and number of captured neutrons of each sample were estimated by using Geant4 Monte Carlo code. As a result, growing boron carbide concentration can raise cross section value of Datolite and galena.","PeriodicalId":94103,"journal":{"name":"Journal of physical chemistry & biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84693327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.4172/2161-0398.1000277
Mamedova Mt
The steam conversion of carbon monoxide, the conjugation of the conversion of ethyl benzene (EB) to styrene (St) with the steam conversion of carbon monoxide (SCCM) and the conversion of ethyl benzene to styrene in the presence of CO2 on a low-temperature magnesium-zirconium catalyst modified with phosphoric acid and copper were studied. It has been established that by the conjugation of conversion of EB to styrene with the steam conversion of carbon monoxide, it is possible to create a highly efficient, environmentally friendly process for the production of styrene and hydrogen with a relatively low expenditure of additional capital and energy.
{"title":"Study of the Conjugation of Ethyl Benzene Dehydrogenation to Styrene with Steam Conversion of Carbon Monoxide on a Magnesium-Zirconium Catalyst","authors":"Mamedova Mt","doi":"10.4172/2161-0398.1000277","DOIUrl":"https://doi.org/10.4172/2161-0398.1000277","url":null,"abstract":"The steam conversion of carbon monoxide, the conjugation of the conversion of ethyl benzene (EB) to styrene (St) with the steam conversion of carbon monoxide (SCCM) and the conversion of ethyl benzene to styrene in the presence of CO2 on a low-temperature magnesium-zirconium catalyst modified with phosphoric acid and copper were studied. It has been established that by the conjugation of conversion of EB to styrene with the steam conversion of carbon monoxide, it is possible to create a highly efficient, environmentally friendly process for the production of styrene and hydrogen with a relatively low expenditure of additional capital and energy.","PeriodicalId":94103,"journal":{"name":"Journal of physical chemistry & biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79349978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-01DOI: 10.4172/2161-0398-C3-033
R. Tuckett
This talk arises from two articles recently accepted for publication by Elsevier in their Reference Modules [1,2]; the first also comes out next year in paper copy in the 3rd edition of Encyclopaedia Analytical Sciences, Written for the intelligent nonexpert, the science of the greenhouse effect and the most up-to-date data are presented in the first article [1]. In summary, the two most significant secondary greenhouse gases remain CO2 and CH4, together they contribute c. 80-85% of the secondary greenhouse effect, and this percentage has not changed for the last 20-30 years. CH4 could indeed prove to be as serious a secondary greenhouse gas as CO2. However, the total radiative forcing which causes the increase in Planet Earth’s temperature has increased consistently over this time window, and the huge majority of the world’s scientists now accept that we have a huge environmental issue on our hands that will not disappear. In the second article [2], suggestions are made as what issues people should think about from individual, government and world positions. The author is a practicing member of the Quaker (Society of Friends) religion, and throughout he comes to this problem from a moral viewpoint. This will not be a talk about religion, but rather how the six Quaker Testimonies (i.e. way we should lead our lives) on Truth and Integrity, Social Justice, Equality, Simplicity, Peace and Sustainability lead him in certain personal directions, and what advice he might give to Governments and World organisations (e.g. the United Nations). A concise and simple explanation of the Quaker religion in the UK in 2017 is written elsewhere [3]; much of it may surprise many delegates! The average temperature of the Earth (red) and the concentration level of CO2 in the Earth’s atmosphere (in red) during the recent history since AD1880. (Stoft http://zfacts.com/p/226.html or Hocker http://wattsupwiththat.com/2010/06/09/). A rise of 1 F is equivalent to 0.56°C. From a scientific viewpoint, there is no proven correlation between the two sets of data. Climate change, broadly interpreted, is a significant and lasting change in the statistical distribution of weather patterns over periods ranging from decades to millions of years. It may be a change in average weather conditions, or in the distribution of weather around the average conditions (such as more or fewer extreme weather events). Climate change is caused by factors that include oceanic processes (such as oceanic circulation), biotic processes (e.g., plants), variations in solar radiation received by Earth, plate tectonics and volcanic eruptions, and human-induced alterations of the natural world. The latter effect is currently causing global warming, and "climate change" is often used to describe human-specific impacts. During the 1970s, scientific opinion increasingly favored the warming viewpoint. From ancient times, people suspected that the climate of a region could change over the course of centuries.
{"title":"Climate change and global warming: thoughts of a Quaker scientist","authors":"R. Tuckett","doi":"10.4172/2161-0398-C3-033","DOIUrl":"https://doi.org/10.4172/2161-0398-C3-033","url":null,"abstract":"This talk arises from two articles recently accepted for publication by Elsevier in their Reference Modules [1,2]; the first also comes out next year in paper copy in the 3rd edition of Encyclopaedia Analytical Sciences, Written for the intelligent nonexpert, the science of the greenhouse effect and the most up-to-date data are presented in the first article [1]. In summary, the two most significant secondary greenhouse gases remain CO2 and CH4, together they contribute c. 80-85% of the secondary greenhouse effect, and this percentage has not changed for the last 20-30 years. CH4 could indeed prove to be as serious a secondary greenhouse gas as CO2. However, the total radiative forcing which causes the increase in Planet Earth’s temperature has increased consistently over this time window, and the huge majority of the world’s scientists now accept that we have a huge environmental issue on our hands that will not disappear. In the second article [2], suggestions are made as what issues people should think about from individual, government and world positions. The author is a practicing member of the Quaker (Society of Friends) religion, and throughout he comes to this problem from a moral viewpoint. This will not be a talk about religion, but rather how the six Quaker Testimonies (i.e. way we should lead our lives) on Truth and Integrity, Social Justice, Equality, Simplicity, Peace and Sustainability lead him in certain personal directions, and what advice he might give to Governments and World organisations (e.g. the United Nations). A concise and simple explanation of the Quaker religion in the UK in 2017 is written elsewhere [3]; much of it may surprise many delegates! The average temperature of the Earth (red) and the concentration level of CO2 in the Earth’s atmosphere (in red) during the recent history since AD1880. (Stoft http://zfacts.com/p/226.html or Hocker http://wattsupwiththat.com/2010/06/09/). A rise of 1 F is equivalent to 0.56°C. From a scientific viewpoint, there is no proven correlation between the two sets of data. Climate change, broadly interpreted, is a significant and lasting change in the statistical distribution of weather patterns over periods ranging from decades to millions of years. It may be a change in average weather conditions, or in the distribution of weather around the average conditions (such as more or fewer extreme weather events). Climate change is caused by factors that include oceanic processes (such as oceanic circulation), biotic processes (e.g., plants), variations in solar radiation received by Earth, plate tectonics and volcanic eruptions, and human-induced alterations of the natural world. The latter effect is currently causing global warming, and \"climate change\" is often used to describe human-specific impacts. During the 1970s, scientific opinion increasingly favored the warming viewpoint. From ancient times, people suspected that the climate of a region could change over the course of centuries.","PeriodicalId":94103,"journal":{"name":"Journal of physical chemistry & biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74517623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-04-01DOI: 10.4172/2161-0398.1000266
H. Banu, Tsodiya Banu Shallangwa, Innocent Joseph, T. Magu, Sadia Ahmed, Louis Hitler
Biofuel is an alternative and environment friendly source of energy, originated by the use of fossil fuels and have led to a notable growing demand from the last few decades. As biodiesel are usually acquired from renewable sources like vegetable and animal oils, for example coconut oil is extracted from the coconut and then characterized for further usage. The aim of this study is to investigate the production of biodiesel from neem oil and to characterize the parameters that affect biodiesel performance. The Biodiesel was produced using trans-esterification process resulting in the values of saponification 191 mg KOH/g, iodine 10 mgl2/g, acid 14.0 mg KOH/g, density 0.91 g, viscosity 23 mm2/s and flash point 266°C. The biodiesel was also characterized and showed that the it has density of 820 kg/m3, viscosity 3.5 mm2/s, saponification value 91 mg KOH/g, iodine value 8.9 mgl2/g, acid content 30.8 mg KOH/g and flash point 110°C. The physicochemical properties obtained were also compared to standard biodiesel in the range of ASTM specifications.
{"title":"Biodiesel Production from Neem Seed ( Azadirachta indica ) Oil Using Calcium Oxide as Heterogeneous Catalyst","authors":"H. Banu, Tsodiya Banu Shallangwa, Innocent Joseph, T. Magu, Sadia Ahmed, Louis Hitler","doi":"10.4172/2161-0398.1000266","DOIUrl":"https://doi.org/10.4172/2161-0398.1000266","url":null,"abstract":"Biofuel is an alternative and environment friendly source of energy, originated by the use of fossil fuels and have led to a notable growing demand from the last few decades. As biodiesel are usually acquired from renewable sources like vegetable and animal oils, for example coconut oil is extracted from the coconut and then characterized for further usage. The aim of this study is to investigate the production of biodiesel from neem oil and to characterize the parameters that affect biodiesel performance. The Biodiesel was produced using trans-esterification process resulting in the values of saponification 191 mg KOH/g, iodine 10 mgl2/g, acid 14.0 mg KOH/g, density 0.91 g, viscosity 23 mm2/s and flash point 266°C. The biodiesel was also characterized and showed that the it has density of 820 kg/m3, viscosity 3.5 mm2/s, saponification value 91 mg KOH/g, iodine value 8.9 mgl2/g, acid content 30.8 mg KOH/g and flash point 110°C. The physicochemical properties obtained were also compared to standard biodiesel in the range of ASTM specifications.","PeriodicalId":94103,"journal":{"name":"Journal of physical chemistry & biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81915334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-04-01DOI: 10.4172/2161-0398.1000267
S. Kim, S. Z. Kim
Resveratrol (RSV) is a polyphenolic compound naturally found in grapes, peanuts, and berries. Considerable research has been performed to determine the benefits of RSV against various human diseases, especially cancer. Despite numerous studies on the effect of RSV on cancer, correct understanding of its mechanism is still far from certainty. This review summarizes the recent results on the molecular mechanisms and pathways of actions of RSV against major cancers. According to investigations accomplished worldwide, RSV targets pathways such as cell cycle progression, autophagy, apoptosis, angiogenesis and invasion/metastasis to attenuate cancer progression mediated through PI3K/Akt/mTOR, Wnt, ROS, NF-κB, BAX/Bcl-2, AMPK, ERK, MAPK signaling pathway. Considering the sideeffects and data of clinical trials, RSV can be used for its maximum benefits in human diseases. Available published data provide strong clues on the impact of RSV on cancer management.
{"title":"Biological Activities of Resveratrol against Cancer","authors":"S. Kim, S. Z. Kim","doi":"10.4172/2161-0398.1000267","DOIUrl":"https://doi.org/10.4172/2161-0398.1000267","url":null,"abstract":"Resveratrol (RSV) is a polyphenolic compound naturally found in grapes, peanuts, and berries. Considerable research has been performed to determine the benefits of RSV against various human diseases, especially cancer. Despite numerous studies on the effect of RSV on cancer, correct understanding of its mechanism is still far from certainty. This review summarizes the recent results on the molecular mechanisms and pathways of actions of RSV against major cancers. According to investigations accomplished worldwide, RSV targets pathways such as cell cycle progression, autophagy, apoptosis, angiogenesis and invasion/metastasis to attenuate cancer progression mediated through PI3K/Akt/mTOR, Wnt, ROS, NF-κB, BAX/Bcl-2, AMPK, ERK, MAPK signaling pathway. Considering the sideeffects and data of clinical trials, RSV can be used for its maximum benefits in human diseases. Available published data provide strong clues on the impact of RSV on cancer management.","PeriodicalId":94103,"journal":{"name":"Journal of physical chemistry & biophysics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73152138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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