Development and Evaluation of Topical Gel with Aloe vera: Novel Treatment of Psoriasis

Abstract

The present studies aim that development and evaluation of topical gel with aloe Vera novel treatment for psoriasis. Topical gel formulation was designed by using Aloe Vera in varied concentration. The gel was prepared by using cyclosporine as drug with other excipients such as carbopol 940, methanol, propylene glycol, methyl paraben, propyl paraben, tri-ethanolamine and required amount of water. The prepared gel was evaluated for physical appearance, PH, spread ability, drug content, swelling index, diffusion study, viscosity, homogenicity, extrudability, and grittiness. It was inferred from that gel formulation were good in appearance and homogenicity. The prepared herbal gel is very useful for the anti proliferative and anti-inflammatory action for the treatment of psoriasis. © 2019 iGlobal Research and Publishing Foundation. All rights reserved. Cite this article as: Kumar, A.; Pandit, V.; Sharma, T. Development and Evaluation of Topical Gel with Aloe vera: Novel Treatment of Psoriasis. Indo Global J. Pharm. Sci., 2019; 9(2Suppl.): 125. DOI: http://doi.org/10.35652/IGJPS.2019.92S23 . Indo Global Journal of Pharmaceutical Sciences( ISSN 2249 1023; CODENIGJPAI; NLM ID: 101610675) indexed and abstracted in CrossRef (DOI Enabling), UGC CARE Journal List, EMBASE(Elsevier), National Library of Medicine (NLM) Catalog, ResearchGate, Publons, CAS (ACS), Index Copernicus, Google Scholar and many more. For further details, visit http://iglobaljournal.com This is a special issue as an outcome of ‘RAPSCON-2019’ sponsored by APTI and organized by Sri Sai College of Pharmacy, Manawala, Amritsar, Punjab, India. Relaxation offered in journal format.