A Novel Generative Adversarial Network simulating the complementary structure of DNA genetic information

Lei Zhang, Haoying Wu
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Abstract

To solve the problems of mode collapse and training instability in generative adversarial networks (GANs), a framework simulating the complementary structure of DNA is proposed, in which a complementary unit and a generalization unit are added. Four latent vectors representing four bases of A, T,C and G are obtained from the complementary unit. Through the combination of latent vectors, the generalization unit avoids the fitting of high-dimensional data distribution and obtains a more comprehensive vector space. Experimental results show that the problems of model collapse and training instability are effectively solved, compared with state-of-the-art VAE-GAN, the FID score increases 52.2%, indicating that the quality and diversity of images generated by the model are improved.
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一种模拟DNA遗传信息互补结构的新型生成对抗网络
为了解决生成对抗网络(GANs)中的模式崩溃和训练不稳定性问题,提出了一种模拟DNA互补结构的框架,在该框架中加入一个互补单元和一个泛化单元。从互补单元得到代表A、T、C和G四种碱基的四个潜在向量。通过潜向量的组合,泛化单元避免了高维数据分布的拟合,得到了更全面的向量空间。实验结果表明,该方法有效地解决了模型崩溃和训练不稳定的问题,与最先进的vee - gan相比,FID得分提高了52.2%,表明该模型生成的图像质量和多样性得到了提高。
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