Therapeutic effects of nerve block combined with radiofrequency ablation on trigeminal nerve pain in oral and maxillofacial region

Zihan Li, Hongpei Wang, Jian Guo, D. Lei
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Abstract

Objective To investigate the clinical effects of nerve block combined with radiofrequency ablation in the treatment of trigeminal pain in oral and maxillofacial region. Methods Eighty patients with trigeminal pain in oral and maxillofacial region admitted to Second Hospital of Lanzhou University from December 2016 to October 2018 were enrolled in the study. The patients were grouped according to the order of admission, of which the first 40 cases were allocated into single group and the latter 40 cases were allocated into combined group. And the single group was treated by nerve block therapy, and the combined group was treated by nerve block combined with radiofrequency surgery. The efficacy, degree of pain before and after treatment, frequency of pain, incidence of adverse reactions, and quality of life were compared between the two groups. Results The excellent and good rate of treatment was 70.00% (28/40) in the single group, and 90.00% (36/40) in the combined group; the difference in excellent and good rate was significant between the two groups (P<0.05). After treatment, the pain scores, frequency of pain onset and quality of life interference scores of the combined group were lower than those of the single group (P<0.05); moreover, the adverse reaction rate of the combined group was 5.00% (2/40), lower than the 25.00% (10/40) of the single group (P<0.05). Conclusions In the treatment of patients with oral and maxillofacial trigeminal pain, nerve block and radiofrequency surgery can effectively improve the pain symptoms, reduce the frequency and degree of pain, reduce the incidence of adverse reactions, and improve the quality of life of patients, with great long-term efficacy. Key words: Nerve block; Oral and maxillofacial; Trigeminal pain; Radiofrequency surgery
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神经阻滞联合射频消融术治疗口腔颌面三叉神经痛的疗效观察
目的探讨神经阻滞联合射频消融术治疗口腔颌面三叉神经痛的临床疗效。方法选取2016年12月至2018年10月兰州大学第二医院收治的80例口腔颌面三叉神经痛患者为研究对象。患者按入院顺序分组,其中前40例为单组,后40例为联合组。单组采用神经阻滞治疗,联合组采用神经阻滞联合射频手术治疗。比较两组患者的疗效、治疗前后疼痛程度、疼痛频次、不良反应发生率及生活质量。结果单药组优良率为70.00%(28/40),联合用药组优良率为90.00% (36/40);两组优良率比较差异有统计学意义(P<0.05)。治疗后,联合治疗组疼痛评分、疼痛发作频率、生活质量干扰评分均低于单独治疗组(P<0.05);联合用药组不良反应发生率为5.00%(2/40),低于单独用药组25.00% (10/40)(P<0.05)。结论在治疗口腔颌面三叉神经痛患者时,神经阻滞联合射频手术可有效改善疼痛症状,降低疼痛频率和程度,减少不良反应的发生,提高患者的生活质量,具有很大的远期疗效。关键词:神经阻滞;口腔颌面;三叉神经疼痛;射频手术
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