Association of Sasang Constitutional Type with Bone Mineral Density, Osteopenia, and Osteoporosis

S. K. Lee, D. Yoon, J. Y. Kim, J. K. Kim, Hyeryeon Yi, Sunghee Lee, R. Abbott, C. Shin
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Abstract

Association of Sasang Constitutional Type with Bone Mineral Density, Osteopenia, and Osteoporosis Seung Ku Lee⋅Dae Wui Yoon⋅Jong Yeol Kim⋅Jin Kwan Kim⋅Hyeryeon Yi⋅ Sunghee Lee⋅Robert D. Abbott⋅Chol Shin Institute of Human Genomic Study, College of Medicine, Korea University Ansan Hospital Department of Biomedical Laboratory Science, College of Health Science, Jungwon University Constitutional Medicine and Diagnosis Research Group, Korea Institute of Oriental Medicine Department of Nursing, Korea Nazarene University Department of Food and Nutrition, College of Health Science, Kangwon National University Department of Pulmonary, Sleep and Critical Care Medicine, College of Medicine, Korea University Ansan Hospital College of Medicine, Korea University Object Although Taeeum and Soyang constitutional types have bigger body shapes and higher body mass index values than those with the Soeum, the relationship between the Sasang constitutional type and bone mass density is controversial and the association of osteopenia and osteoporosis remains unknown. Therefore, we investigated the relationship between bone mineral density, osteopenia, and osteoporosis according to Sasang constitutional type. Methods A total of 2,508 participants were included in this study. Among the study participants, 1,396 had Taeeum type, 276 had Soeum type, and 836 had Soyang type, respectively. The relationships to bone mass density, osteopenia, and osteoporosis in those with Sasang constitutional type were estimated using logistic and linear regression models. Results Bone mass density was significantly higher in the order of Taeeum, Soyang, and Soeum group (p < 0.01). Soeum group in comparison with Taeeum or Soyang group was significantly associated with a high odds ratio for osteopenia and osteoporosis except in the hip and femoral neck in the comparison of Taeeum and Soeum group (p < 0.01). Moreover, the bone mass density of Soeum group decreased more rapidly as the age increased when compared with Taeeum and Soyang group. Conclusions Our findings may contribute to the early prevention and management of high-risk individuals with poor bone mass density, osteopenia, and osteoporosis using Sasang constitution medicine.
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Sasang体质类型与骨密度、骨质减少和骨质疏松症的关系
Sasang体质类型与骨密度、骨质减少、骨质疏松症的关联李承九⋅⋅Wui Yoon⋅Jong Yeol Kim⋅Jin Kwan Kim⋅Hyeryeon Yi⋅Sunghee Lee⋅Robert D. Abbott⋅Chol Shin高丽大学安山医院医学院生物医学实验科学部、中原大学体质医学与诊断研究组、韩国东方医学研究院护理系韩国拿撒勒大学食品营养系、保健学院、江原大学肺、睡眠、重症医学系、高丽大学安山医院医学院、高丽大学医学院研究对象:虽然太音型和西阳型体质比西音型体型更大,体质指数也更高,Sasang体质类型和骨密度之间的关系是有争议的,骨质减少和骨质疏松的关系仍然未知。因此,我们根据Sasang体质类型研究骨密度、骨质减少和骨质疏松症之间的关系。方法共纳入2508名被试。研究对象中,太阴型1396人,苏阴型276人,西阳型836人。使用logistic和线性回归模型估计Sasang体质型患者骨量密度、骨质减少和骨质疏松症的关系。结果太阴组、索阳组、索阳组骨密度显著高于对照组(p < 0.01)。除髋关节和股骨颈外,Soeum组与taeum组和Soyang组相比,Soeum组与Soeum组骨质减少和骨质疏松症的比值比均显著升高(p < 0.01)。随着年龄的增长,Soeum组的骨密度比taeum和Soyang组下降得更快。结论本研究结果可为早期预防和管理低骨密度、骨质减少和骨质疏松的高危人群使用沙桑体质药提供依据。
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