Anterior Cruciate Ligament Reconstruction with Platelet Rich Plasma: Systematic Review

Fernández Laura, Seijas Roberto, P. Albert, Ragazzi Paolo, P. Olivier, Alvarez Pedro
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Abstract

Objective: The aim of this study was reviewed the scientific evidence of the relationship that could exist between the use of Platelet Rich Plasma (PRP) after the reconstruction of the Anterior Cruciate Ligament (ACL). Design: We performed a systematic using the following key words: platelet rich plasma AND anterior cruciate ligament. Abstracts were screened by a single reviewer. For those studies meeting the eligibility criteria, full-text articles were obtained. Results: From 127 studies found only 5 articles were included in this systematic review. We found the presence of inflammatory diseases, DM, advanced osteoarthrosis (grade III-IV), previous knee surgeries, malignant diseases, contrast allergy, renal disease and thrombocytopenia. Conclusion: The use of the platelet rich plasma after the ACL reconstruction with patellar tendon, demonstrates a better autograft recovery in terms of vascularization, bone remodeling and edema decreasing, achieving an earlier autograft homogenization.
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富血小板血浆重建前交叉韧带:系统综述
目的:综述富血小板血浆(PRP)在前交叉韧带(ACL)重建后应用的科学依据。设计:我们对富血小板血浆和前交叉韧带进行了系统的研究。摘要由一名审稿人筛选。对于那些符合资格标准的研究,获得了全文文章。结果:从127项研究中发现,只有5篇文章被纳入本系统综述。我们发现存在炎症性疾病、糖尿病、晚期骨关节病(III-IV级)、既往膝关节手术、恶性疾病、对比剂过敏、肾脏疾病和血小板减少症。结论:髌腱重建前交叉韧带后使用富血小板血浆,在血管形成、骨重塑和水肿减少方面显示出更好的自体移植物恢复,实现了早期的自体移植物均匀化。
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