P. Selvamani, Venkata Krishnan Par, Rosi Rajamanickam, S. Latha
{"title":"MAGNETIC NANOLIPOSOMES: A REVIEW ON PREPARATION AND CHARACTERIZATION METHODS","authors":"P. Selvamani, Venkata Krishnan Par, Rosi Rajamanickam, S. Latha","doi":"10.21276/bpr.2021.11.3","DOIUrl":null,"url":null,"abstract":"Magnetic nanoliposomes are versatile nanocarriers for targeted drug delivery. These liposomes can enhance the efficacy of bioactive compounds by improving pharmacokinetic parameters. Chemical ingredients of magnetic nanoliposomes include ferrofluid, cholesterol and phospholipid molecules. The preparation of magnetic nanoliposomes involves two steps viz. synthesis of magnetic nanoparticles and then combination with prepared nanoliposomes. The magnetic nanoliposomes are synthesized by various chemical methods including co-precipitation, thermal decomposition, microemulsion and hydrothermal synthesis. The nanoliposomes are prepared by sonication, extrusion, micro-fluidization techniques. Characterization studies included size, nanoparticle tracking analysis, flow cytometry, size exclusion chromatography, DSC, encapsulation efficiency. This study provides an overview of the preparation and characterization techniques of magnetic nanoliposomes.","PeriodicalId":9368,"journal":{"name":"Bulletin of Pharmaceutical Research Institute","volume":"41 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of Pharmaceutical Research Institute","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21276/bpr.2021.11.3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Magnetic nanoliposomes are versatile nanocarriers for targeted drug delivery. These liposomes can enhance the efficacy of bioactive compounds by improving pharmacokinetic parameters. Chemical ingredients of magnetic nanoliposomes include ferrofluid, cholesterol and phospholipid molecules. The preparation of magnetic nanoliposomes involves two steps viz. synthesis of magnetic nanoparticles and then combination with prepared nanoliposomes. The magnetic nanoliposomes are synthesized by various chemical methods including co-precipitation, thermal decomposition, microemulsion and hydrothermal synthesis. The nanoliposomes are prepared by sonication, extrusion, micro-fluidization techniques. Characterization studies included size, nanoparticle tracking analysis, flow cytometry, size exclusion chromatography, DSC, encapsulation efficiency. This study provides an overview of the preparation and characterization techniques of magnetic nanoliposomes.
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