{"title":"FORMULATION AND EVALUATION OF LEVOCETIRIZINE TOPICAL GEL","authors":"C. P.","doi":"10.21276/bpr.2022.12.2","DOIUrl":"https://doi.org/10.21276/bpr.2022.12.2","url":null,"abstract":"","PeriodicalId":9368,"journal":{"name":"Bulletin of Pharmaceutical Research Institute","volume":"97 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86022032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"INVESTIGATING SYNERGISTIC ACTIVITY OF METHANOLIC EXTRACT OF CURCUMA LONGA AND MORINGA OLIFERA FOR IN VITRO ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES","authors":"T. S, Omini M, B. A, B. P., L. K, P. S.","doi":"10.21276/bpr.2022.12.3","DOIUrl":"https://doi.org/10.21276/bpr.2022.12.3","url":null,"abstract":"","PeriodicalId":9368,"journal":{"name":"Bulletin of Pharmaceutical Research Institute","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89696090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ORAL ANTIVIRAL MEDICINES FOR COVID-19","authors":"Colon Kr, Dahiya S","doi":"10.21276/bpr.2022.12.1","DOIUrl":"https://doi.org/10.21276/bpr.2022.12.1","url":null,"abstract":"","PeriodicalId":9368,"journal":{"name":"Bulletin of Pharmaceutical Research Institute","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73677169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Selvamani, Venkata Krishnan Par, Rosi Rajamanickam, S. Latha
Magnetic nanoliposomes are versatile nanocarriers for targeted drug delivery. These liposomes can enhance the efficacy of bioactive compounds by improving pharmacokinetic parameters. Chemical ingredients of magnetic nanoliposomes include ferrofluid, cholesterol and phospholipid molecules. The preparation of magnetic nanoliposomes involves two steps viz. synthesis of magnetic nanoparticles and then combination with prepared nanoliposomes. The magnetic nanoliposomes are synthesized by various chemical methods including co-precipitation, thermal decomposition, microemulsion and hydrothermal synthesis. The nanoliposomes are prepared by sonication, extrusion, micro-fluidization techniques. Characterization studies included size, nanoparticle tracking analysis, flow cytometry, size exclusion chromatography, DSC, encapsulation efficiency. This study provides an overview of the preparation and characterization techniques of magnetic nanoliposomes.
{"title":"MAGNETIC NANOLIPOSOMES: A REVIEW ON PREPARATION AND CHARACTERIZATION METHODS","authors":"P. Selvamani, Venkata Krishnan Par, Rosi Rajamanickam, S. Latha","doi":"10.21276/bpr.2021.11.3","DOIUrl":"https://doi.org/10.21276/bpr.2021.11.3","url":null,"abstract":"Magnetic nanoliposomes are versatile nanocarriers for targeted drug delivery. These liposomes can enhance the efficacy of bioactive compounds by improving pharmacokinetic parameters. Chemical ingredients of magnetic nanoliposomes include ferrofluid, cholesterol and phospholipid molecules. The preparation of magnetic nanoliposomes involves two steps viz. synthesis of magnetic nanoparticles and then combination with prepared nanoliposomes. The magnetic nanoliposomes are synthesized by various chemical methods including co-precipitation, thermal decomposition, microemulsion and hydrothermal synthesis. The nanoliposomes are prepared by sonication, extrusion, micro-fluidization techniques. Characterization studies included size, nanoparticle tracking analysis, flow cytometry, size exclusion chromatography, DSC, encapsulation efficiency. This study provides an overview of the preparation and characterization techniques of magnetic nanoliposomes.","PeriodicalId":9368,"journal":{"name":"Bulletin of Pharmaceutical Research Institute","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90958237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Gupta, Anurag Mishra, Sachchidanand Pathak, S. Singh, Himmat Singh, R. Dahiya
{"title":"ROLE OF PI3K/AKT PATHWAY IN PROTECTION OF ISONIAZID/RIFAMPICIN-INDUCED HEPATOTOXICITY: A PHARMACOLOGICAL APPROACH","authors":"G. Gupta, Anurag Mishra, Sachchidanand Pathak, S. Singh, Himmat Singh, R. Dahiya","doi":"10.21276/bpr.2021.11.1","DOIUrl":"https://doi.org/10.21276/bpr.2021.11.1","url":null,"abstract":"","PeriodicalId":9368,"journal":{"name":"Bulletin of Pharmaceutical Research Institute","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77722401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ANTIBACTERIAL ACTIVITY STUDIES ON PAPAYA LEAVES AND ORANGE PEELS AGAINST COMMON BACTERIAL SPECIES","authors":"Ramona Alfred Vas, P. Patil, S. Pandey","doi":"10.21276/bpr.2021.11.2","DOIUrl":"https://doi.org/10.21276/bpr.2021.11.2","url":null,"abstract":"","PeriodicalId":9368,"journal":{"name":"Bulletin of Pharmaceutical Research Institute","volume":"83 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91445367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peptides and proteins are vital biomacromolecules that perform several bodily functions in various physiological and biological processes. Being biocompatible and biodegradable, these macromolecules are considered promising platforms for delivery of drugs and genes. However, peptides and proteins suffer from major limitations including enzymatic degradation, short circulation half-lives, and poor membrane permeability that leads to poor bioavailability, challenging their effective delivery. This article briefly discusses the inherent challenges in peptide and protein delivery along with strategies for bioavailability enhancement and lipid nanocarriers as prospective systems for peptide and protein drug delivery.
{"title":"BIOAVAILABILITY ENHANCEMENT AND LIPID NANOCARRIER BASED DELIVERY OF PEPTIDES AND PROTEINS","authors":"S. Dahiya, R. Dahiya","doi":"10.21276/bpr.2020.10.3","DOIUrl":"https://doi.org/10.21276/bpr.2020.10.3","url":null,"abstract":"Peptides and proteins are vital biomacromolecules that perform several bodily functions in various physiological and biological processes. Being biocompatible and biodegradable, these macromolecules are considered promising platforms for delivery of drugs and genes. However, peptides and proteins suffer from major limitations including enzymatic degradation, short circulation half-lives, and poor membrane permeability that leads to poor bioavailability, challenging their effective delivery. This article briefly discusses the inherent challenges in peptide and protein delivery along with strategies for bioavailability enhancement and lipid nanocarriers as prospective systems for peptide and protein drug delivery.","PeriodicalId":9368,"journal":{"name":"Bulletin of Pharmaceutical Research Institute","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74020161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DEVELOPMENT AND VALIDATION OF NEW RP-HPLC METHOD FOR QUANTITATIVE ESTIMATION OF GUAIFENESIN IN TABLET DOSAGE FORM","authors":"Punagoti Ra, Getaw Ns, R. Mourya","doi":"10.21276/bpr.2019.9.4","DOIUrl":"https://doi.org/10.21276/bpr.2019.9.4","url":null,"abstract":"","PeriodicalId":9368,"journal":{"name":"Bulletin of Pharmaceutical Research Institute","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90050318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"INCIDENCE AND ANTIBIOTIC SENSITIVITY PATTERNS OF HAEMOLYTIC STRAINS OF STAPHYLOCOCCUS AUREUS ISOLATED FROM THE ENVIRONMENTS OF PAEDIATRIC WARDS OF SELECTED HOSPITALS IN OSOGBO, OSUN STATE, NIGERIA","authors":"Alalade Ob, Adeosun Ij, Ajayeoba Ta","doi":"10.21276/bpr.2019.9.3","DOIUrl":"https://doi.org/10.21276/bpr.2019.9.3","url":null,"abstract":"","PeriodicalId":9368,"journal":{"name":"Bulletin of Pharmaceutical Research Institute","volume":"164 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77482187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ISOLATION OF BETA-ASARONE AND FORSKOLIN AND THEIR IN VIVO ACTIVITY AGAINST STRESS","authors":"Tiwari N","doi":"10.21276/bpr.2019.9.2","DOIUrl":"https://doi.org/10.21276/bpr.2019.9.2","url":null,"abstract":"","PeriodicalId":9368,"journal":{"name":"Bulletin of Pharmaceutical Research Institute","volume":"119 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74238981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}