Epidemiology and awareness of osteoporosis: a viewpoint from the Middle East and North Africa

T. Hammam
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引用次数: 33

Abstract

Background: Osteoporosis (OP) is defined by low bone mass and microstructural deterioration. It is an escalating public health problem due to increase life expectancy and the resulting bone fractures represent a significant burden for both the individual and the society in terms of morbidity, mortality and cost. Osteoporosis, a multifactorial disease, results from the interaction between genetic and environmental risk factors. Currently, the data available regarding OP epidemiology and predisposing risk factors differ greatly between regions and within population ethnicities. Proper estimation of the epidemiology of OP and its health related outcomes can help identity those at risk and permit prophylactic treatment before its occurrence. The main barrier towards disease prevention strategies is the impaired awareness of the disease and its risk. Enhanced understanding of the OP disease may influence personal behaviors and reduce its prevalence. Objectives: This review was undertaken to wrap-up and throw-light on the published literatures related to the epidemiology of osteoporosis in the Middle East and North Africa (MENA) region, and expose the extent of awareness in the corresponding populations. Describing and discussing key points on the current state of knowledge on these hot issues are well thought-out. Conclusion: Osteoporosis prevalence is variable among MENA populations. Limited reports regarding the established prevalence of osteoporotic fractures among those populations and therefore, lack of guidelines for prevention and management were noticed. In order to improve bone health, preventive measures against OP should be considered. Increase OP awareness and preventive practices in the societies as part of the prophylactic strategy need to be initiated.
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骨质疏松症的流行病学和认识:来自中东和北非的观点
背景:骨质疏松症(Osteoporosis, OP)是指骨量低和显微结构恶化。由于预期寿命延长,这是一个不断升级的公共卫生问题,由此导致的骨折在发病率、死亡率和费用方面对个人和社会都是一个重大负担。骨质疏松症是一种多因素疾病,是遗传和环境危险因素相互作用的结果。目前,关于OP流行病学和易感危险因素的现有数据在地区和人口种族之间存在很大差异。正确估计OP的流行病学及其与健康相关的结果可以帮助识别高危人群,并在其发生之前进行预防性治疗。实施疾病预防战略的主要障碍是对疾病及其风险的认识不足。加强对OP疾病的了解可能会影响个人行为并减少其患病率。目的:对中东和北非(MENA)地区骨质疏松症流行病学相关的已发表文献进行总结和梳理,并揭示相应人群对骨质疏松症的认识程度。描述和讨论这些热点问题的知识现状的关键点是深思熟虑的。结论:骨质疏松症患病率在中东和北非地区人群中存在差异。关于骨质疏松性骨折在这些人群中发病率的报道有限,因此缺乏预防和管理的指南。为了改善骨骼健康,应考虑对OP的预防措施。作为预防战略的一部分,需要在社会中提高对口服避孕药的认识和预防措施。
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