Outcomes of Surgical Management for Parathyroid Adenomas.

IF 0.3 3区文学 0 LITERATURE SUB-STANCE Pub Date : 2023-12-01 Epub Date: 2023-06-27 DOI:10.1007/s12070-023-04006-7

Gargi Dhingani, Akshat Malik, Vikram Singh, Harit Chaturvedi, Rohit Nayyar

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Abstract

Aim: Descriptive analysis of patients undergoing parathyroid adenoma surgery at a tertiary care hospital.

Methodology: Patients with parathyroid adenoma operated from January 2016 to December 2020. Serum calcium and PTH were used to establish the diagnosis. Ultrasonography (USG) studies localized the adenoma. NIH criteria was used for decision regarding surgery. Patients were analyzed with regards to pre operative localization, biochemical monitoring and other outcomes.

Results: Of the 15 eligible patients, all were symptomatic, with myalgia (34%) being the commonest symptom. Rome criteria confirmed the adequacy of the procedure by measuring intra operative drop in PTH. Average decrease in serum PTH level was 69.9% and serum calcium was 20.6% after excision of adenoma. The average size of excised adenoma was 2.5 cm. There were no post operative complications and all patients were normocalcemic on follow up.

Conclusion: Parathyroidectomy is a simple, safe and effective solution that reduces the morbidity of symptomatic primary hyperparathyroidism patients. Pre operative localization studies affirm the diagnosis and intra operative biochemical confirmation clinches the adequacy of resection.

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甲状旁腺瘤手术治疗的结果。

目的:对三级医院甲状旁腺瘤手术患者进行描述性分析。方法:2016年1月至2020年12月手术的甲状旁腺瘤患者。采用血清钙、甲状旁腺素作为诊断依据。超声检查(USG)可以定位腺瘤。采用NIH标准决定是否进行手术。对患者术前定位、生化监测等结果进行分析。结果:在15例符合条件的患者中，所有患者都有症状，肌痛(34%)是最常见的症状。Rome标准通过测量术中甲状旁腺激素的下降证实了手术的充分性。腺瘤切除后血清PTH水平平均下降69.9%，血清钙平均下降20.6%。切除腺瘤的平均大小为2.5 cm。术后无并发症，随访全部患者血钙正常。结论:甲状旁腺切除术是一种简单、安全、有效的治疗方法，可降低有症状的原发性甲状旁腺功能亢进患者的发病率。术前定位研究证实了诊断，术中生化确认确定了切除的充分性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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SUB-STANCE LITERATURE-

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期刊介绍： SubStance has a long-standing reputation for publishing innovative work on literature and culture. While its main focus has been on French literature and continental theory, the journal is known for its openness to original thinking in all the discourses that interact with literature, including philosophy, natural and social sciences, and the arts. Join the discerning readers of SubStance who enjoy crossing borders and challenging limits.

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