A Brief Review of Radioactive Materials for Therapeutic and Diagnostic Purposes.

IF 1.5 4区 医学 Q3 PHARMACOLOGY & PHARMACY Current radiopharmaceuticals Pub Date : 2023-01-01 DOI:10.2174/1874471016666221028110222
Manisha Bharti, Md Aftab Alam, G S N Koteshewr Rao, Pramod Kumar Sharma
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Abstract

Radiation treatment has been advancing ever since the discovery of X-rays in 1895. The goal of radiotherapy is to shape the best isodose on the tumor volume while preserving normal tissues. There are three advantages: patient cure, organ preservation, and cost-effectiveness. Randomized trials in many various forms of cancer (including breast, prostate, and rectum) with a high degree of scientific proof confirmed radiotherapy's effectiveness and tolerance. Such accomplishments, critical to patients' quality of life, have been supported in the past. Radiopharmaceuticals were developed to diagnose and treat various disorders, including hyperthyroidism, bone discomfort, cancer of the thyroid gland, and other conditions like metastases, renal failure, and myocardial infarction and cerebral infarction perfusion. It is also possible to sterilize thermo-labile materials with a radioactive substance. This includes surgical dressings and a wide range of other medical supplies. Nuclear medicine provides various advantages, including tumor localization, safe diagnosis, no radiation buildup, and excellent treatment effectiveness. Nowadays, the field of nuclear pharmacy is focused on developing novel radioactive pharmaceutical substances that will be useful.

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放射性材料在治疗和诊断中的应用综述。
自从1895年发现x射线以来,放射治疗一直在进步。放射治疗的目标是在保留正常组织的同时在肿瘤体积上形成最佳等剂量。有三个优点:患者治愈、器官保存和成本效益。许多不同形式的癌症(包括乳腺癌、前列腺癌和直肠癌)的随机试验都有高度的科学证据,证实了放疗的有效性和耐受性。这些成就对患者的生活质量至关重要,过去一直得到支持。放射性药物被用于诊断和治疗各种疾病,包括甲状腺功能亢进、骨骼不适、甲状腺癌以及其他疾病,如转移、肾衰竭、心肌梗死和脑梗死灌注。也可以用放射性物质对热不稳定材料进行灭菌。这包括外科敷料和各种其他医疗用品。核医学具有肿瘤定位、诊断安全、无辐射积聚、治疗效果好等优点。目前,核药学研究的重点是开发具有实用价值的新型放射性药物。
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来源期刊
Current radiopharmaceuticals
Current radiopharmaceuticals PHARMACOLOGY & PHARMACY-
CiteScore
3.20
自引率
4.30%
发文量
43
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