Hassan Dana, Vahid Marmari, Ghanbar Mahmoodi, H. Mahmoodzadeh, M. Ebrahimi, Narges Mehm, Oost
{"title":"CD166 as a stem cell marker? a potential target for therapy colorectal cancer?","authors":"Hassan Dana, Vahid Marmari, Ghanbar Mahmoodi, H. Mahmoodzadeh, M. Ebrahimi, Narges Mehm, Oost","doi":"10.15406/JSRT.2016.01.00041","DOIUrl":null,"url":null,"abstract":"CD166 (Activated leukocyte cell adhesion molecule (ALCAM)) is a member of the immunoglobulin superfamily, which expressed by various cells in several tissues including colorectal cancer (CRC). Many studies have reported the prognostic predictive value of CD166 as a cancer stem cell marker in CRC. CD166 gained increasing attention regarding tumor progression and metastatic spread in CRC. CD166 potentially represents either diagnostic or therapeutic capacities for CRC. This Mini review aimed to clarify the role and significance of CD166 expression in CRC.","PeriodicalId":91560,"journal":{"name":"Journal of stem cell research & therapeutics","volume":"56 4","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2016-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"7","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of stem cell research & therapeutics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15406/JSRT.2016.01.00041","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7
Abstract
CD166 (Activated leukocyte cell adhesion molecule (ALCAM)) is a member of the immunoglobulin superfamily, which expressed by various cells in several tissues including colorectal cancer (CRC). Many studies have reported the prognostic predictive value of CD166 as a cancer stem cell marker in CRC. CD166 gained increasing attention regarding tumor progression and metastatic spread in CRC. CD166 potentially represents either diagnostic or therapeutic capacities for CRC. This Mini review aimed to clarify the role and significance of CD166 expression in CRC.
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