{"title":"Susceptibility and resistance pattern of bacterial isolates and development of antibiogram in a tertiary care hospital of western India","authors":"J. Vaghasiya","doi":"10.55522/jmpas.v12i1.3987","DOIUrl":null,"url":null,"abstract":"The main issue in India and at a global level that led to antibiotic resistance is misuse, irrational prescribing of antibiotics, and lack of sufficient data on antibiotic resistance at a local, regional, and national level to develop antibiotic policy that guides all healthcare professional while prescribing antibiotics. The present study was carried out for 12 months in a tertiary care teaching hospital in western India to develop an antibiogram and to check antimicrobial resistance trends in the hospital. Out of 500 patients, 53.6% were male and 46.4% were female patients. A total of 17 bacterial species were identified throughout the study with gram-negative species infections being most common in hospitals. Escherichia coli was the most frequently isolated gram-negative species. Ceftriaxone was most prescribed frequently followed by amoxicillin and azithromycin, respectively. In the gram-positive organism, ceftriaxone and amoxicillin resistance rate was 65.35% and 35% respectively. Overall, in the study Cceftriaxone (58%) and amoxicillin-clavulanic acid (38.9%), Azithromycin (56%), and ciprofloxacin (53%) were found most resistant antibiotics, and Amikacin (72%), Clindamycin (18%) were most sensitive. Gram-negative infections were identified mostly and cephalosporine and fluoroquinolones antibiotics were showing high antibiotic resistance. An institutional hospital antibiogram was developed to check local antimicrobial agents for various bacteria.","PeriodicalId":16445,"journal":{"name":"Journal of Medical pharmaceutical and allied sciences","volume":"49 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical pharmaceutical and allied sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.55522/jmpas.v12i1.3987","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
The main issue in India and at a global level that led to antibiotic resistance is misuse, irrational prescribing of antibiotics, and lack of sufficient data on antibiotic resistance at a local, regional, and national level to develop antibiotic policy that guides all healthcare professional while prescribing antibiotics. The present study was carried out for 12 months in a tertiary care teaching hospital in western India to develop an antibiogram and to check antimicrobial resistance trends in the hospital. Out of 500 patients, 53.6% were male and 46.4% were female patients. A total of 17 bacterial species were identified throughout the study with gram-negative species infections being most common in hospitals. Escherichia coli was the most frequently isolated gram-negative species. Ceftriaxone was most prescribed frequently followed by amoxicillin and azithromycin, respectively. In the gram-positive organism, ceftriaxone and amoxicillin resistance rate was 65.35% and 35% respectively. Overall, in the study Cceftriaxone (58%) and amoxicillin-clavulanic acid (38.9%), Azithromycin (56%), and ciprofloxacin (53%) were found most resistant antibiotics, and Amikacin (72%), Clindamycin (18%) were most sensitive. Gram-negative infections were identified mostly and cephalosporine and fluoroquinolones antibiotics were showing high antibiotic resistance. An institutional hospital antibiogram was developed to check local antimicrobial agents for various bacteria.