Kinetics of Phenotype Modification Therapy with VISTA: A Retrospective Case Series Using 3D Digital Analysis

IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE International Journal of Periodontics & Restorative Dentistry Pub Date : 2023-05-01 DOI:10.11607/prd.5621
Seiko Min, Yen-Chun Wang, Junya Hamaguchi, Chi-Ching Chang, Taewan Kim, Goncalo Carames, Alfonso Gil, Satoshi Yamaguchi, Satoshi Imazato, Nikola Angelov
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引用次数: 1

Abstract

Phenotype modification therapy has emerged as one of the main treatment objectives of periodontal plastic surgery. However, long-term data on the stability of gingival thickness gains are not available. This study examined the kinetics of mucosal thickness gain as a measure of phenotype modification therapy following treatment of multiple gingival recession defects with vestibular incision subperiosteal tunnel access (VISTA). Six patients with 14 recession type (RT) II teeth were treated using VISTA and subepithelial connective tissue grafts (SCTG). Scanned images of study casts at pre- and postoperative periods (6 to 66 months) were digitally superimposed for quantitative evaluation of soft tissue dimensional changes. Mucosal thickness gains ranged from 1.0 ± 0.7 mm (1 mm apical to cement-enamel junction [CEJ]) to 1.4 ± 0.4 mm (5 mm apical to CEJ). The gingival thickness gains remained relatively stable, with thickness gains at 66 months of 0.5 ± 0.8, 0.9 ± 0.6, 1.1 ± 0.6, 1.0 ± 0.4, and 1.2 ± 0.6 mm at 1, 2, 3, 4 and 5 mm apical to the CEJ, respectively. Treatment of multiple gingival recession defects with VISTA and SCTG led to stable gingival thickness gains and shows promise as a strategy for phenotype modification therapy.

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用VISTA进行表型修饰治疗的动力学:使用3D数字分析的回顾性病例系列
表型修饰治疗已成为牙周整形手术的主要治疗目标之一。然而,关于牙龈厚度增加的稳定性的长期数据是不可用的。本研究考察了采用前庭切口骨膜下隧道通道(VISTA)治疗多发性牙龈退缩缺陷后,粘膜厚度增加的动力学作为表型修饰疗法的测量指标。采用VISTA联合上皮下结缔组织(SCTG)移植治疗6例退行型(RT)ⅱ牙14颗。术前和术后(6至66个月)的研究模型扫描图像进行数字叠加,以定量评估软组织尺寸变化。粘膜厚度增加范围从1.0±0.7 mm(根尖到水泥-牙釉质交界处1 mm [CEJ])到1.4±0.4 mm(根尖到CEJ 5 mm)。牙龈厚度的增加相对稳定,在66个月时,牙龈厚度的增加分别为0.5±0.8、0.9±0.6、1.1±0.6、1.0±0.4和1.2±0.6 mm,分别为1、2、3、4和5 mm。用VISTA和SCTG治疗多发性牙龈退缩缺陷导致稳定的牙龈厚度增加,并显示出作为表型修饰治疗策略的希望。
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来源期刊
CiteScore
2.90
自引率
6.20%
发文量
113
审稿时长
6-12 weeks
期刊介绍: The International Journal of Periodontics & Restorative Dentistry will publish manuscripts concerned with all aspects of clinical periodontology, restorative dentistry, and implantology. This includes pertinent research as well as clinical methodology (their interdependence and relationship should be addressed where applicable); proceedings of relevant symposia or conferences; and quality review papers. Original manuscripts are considered for publication on the condition that they have not been published or submitted for publication elsewhere.
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