Impact of a social prescribing intervention in North East England on adults with type 2 diabetes: the SPRING_NE multimethod study.

Suzanne Moffatt, John Wildman, Tessa M Pollard, Kate Gibson, Josephine M Wildman, Nicola O'Brien, Bethan Griffith, Stephanie L Morris, Eoin Moloney, Jayne Jeffries, Mark Pearce, Wael Mohammed
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Evidence for its effectiveness and how it is experienced by link workers and clients is lacking.</p><p><strong>Objectives: </strong>To evaluate the impact and costs of a link worker social prescribing intervention on health and health-care costs and utilisation and to observe link worker delivery and patient engagement.</p><p><strong>Data sources: </strong>Quality Outcomes Framework and Secondary Services Use data.</p><p><strong>Design: </strong>Multimethods comprising (1) quasi-experimental evaluation of effects of social prescribing on health and health-care use, (2) cost-effectiveness analysis, (3) ethnographic methods to explore intervention delivery and receipt, and (4) a supplementary interview study examining intervention impact during the first UK COVID-19 lockdown (April-July 2020).</p><p><strong>Study population and setting: </strong>Community-dwelling adults aged 40-74 years with type 2 diabetes and link workers in a socioeconomically deprived locality of North East England, UK.</p><p><strong>Intervention: </strong>Link worker social prescribing to improve health and well-being-related outcomes among people with long-term conditions.</p><p><strong>Participants: </strong>(1) Health outcomes study, approximately <i>n</i> = 8400 patients; EuroQol-5 Dimensions, five-level version (EQ-5D-5L), study, <i>n</i> = 694 (baseline) and <i>n</i> = 474 (follow-up); (2) ethnography, <i>n</i> = 20 link workers and <i>n</i> = 19 clients; and COVID-19 interviews, <i>n</i> = 14 staff and <i>n</i> = 44 clients.</p><p><strong>Main outcome measures: </strong>The main outcome measures were glycated haemoglobin level (HbA<sub>1c</sub>; primary outcome), body mass index, blood pressure, cholesterol level, smoking status, health-care costs and utilisation, and EQ-5D-5L score.</p><p><strong>Results: </strong>Intention-to-treat analysis of approximately 8400 patients in 13 intervention and 11 control general practices demonstrated a statistically significant, although not clinically significant, difference in HbA<sub>1c</sub> level (-1.11 mmol/mol) and a non-statistically significant 1.5-percentage-point reduction in the probability of having high blood pressure, but no statistically significant effects on other outcomes. Health-care cost estimates ranged from £18.22 (individuals with one extra comorbidity) to -£50.35 (individuals with no extra comorbidity). A statistically non-significant shift from unplanned (non-elective and accident and emergency admissions) to planned care (elective and outpatient care) was observed. Subgroup analysis showed more benefit for individuals living in more deprived areas, for the ethnically white and those with fewer comorbidities. The mean cost of the intervention itself was £1345 per participant; the incremental mean health gain was 0.004 quality-adjusted life-years (95% confidence interval -0.022 to 0.029 quality-adjusted life-years); and the incremental cost-effectiveness ratio was £327,250 per quality-adjusted life-year gained. 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引用次数: 1

Abstract

Background: Link worker social prescribing enables health-care professionals to address patients' non-medical needs by linking patients into various services. Evidence for its effectiveness and how it is experienced by link workers and clients is lacking.

Objectives: To evaluate the impact and costs of a link worker social prescribing intervention on health and health-care costs and utilisation and to observe link worker delivery and patient engagement.

Data sources: Quality Outcomes Framework and Secondary Services Use data.

Design: Multimethods comprising (1) quasi-experimental evaluation of effects of social prescribing on health and health-care use, (2) cost-effectiveness analysis, (3) ethnographic methods to explore intervention delivery and receipt, and (4) a supplementary interview study examining intervention impact during the first UK COVID-19 lockdown (April-July 2020).

Study population and setting: Community-dwelling adults aged 40-74 years with type 2 diabetes and link workers in a socioeconomically deprived locality of North East England, UK.

Intervention: Link worker social prescribing to improve health and well-being-related outcomes among people with long-term conditions.

Participants: (1) Health outcomes study, approximately n = 8400 patients; EuroQol-5 Dimensions, five-level version (EQ-5D-5L), study, n = 694 (baseline) and n = 474 (follow-up); (2) ethnography, n = 20 link workers and n = 19 clients; and COVID-19 interviews, n = 14 staff and n = 44 clients.

Main outcome measures: The main outcome measures were glycated haemoglobin level (HbA1c; primary outcome), body mass index, blood pressure, cholesterol level, smoking status, health-care costs and utilisation, and EQ-5D-5L score.

Results: Intention-to-treat analysis of approximately 8400 patients in 13 intervention and 11 control general practices demonstrated a statistically significant, although not clinically significant, difference in HbA1c level (-1.11 mmol/mol) and a non-statistically significant 1.5-percentage-point reduction in the probability of having high blood pressure, but no statistically significant effects on other outcomes. Health-care cost estimates ranged from £18.22 (individuals with one extra comorbidity) to -£50.35 (individuals with no extra comorbidity). A statistically non-significant shift from unplanned (non-elective and accident and emergency admissions) to planned care (elective and outpatient care) was observed. Subgroup analysis showed more benefit for individuals living in more deprived areas, for the ethnically white and those with fewer comorbidities. The mean cost of the intervention itself was £1345 per participant; the incremental mean health gain was 0.004 quality-adjusted life-years (95% confidence interval -0.022 to 0.029 quality-adjusted life-years); and the incremental cost-effectiveness ratio was £327,250 per quality-adjusted life-year gained. Ethnographic data showed that successfully embedded, holistic social prescribing providing supported linking to navigate social determinants of health was challenging to deliver, but could offer opportunities for improving health and well-being. However, the intervention was heterogeneous and was shaped in unanticipated ways by the delivery context. Pressures to generate referrals and meet targets detracted from face-to-face contact and capacity to address setbacks among those with complex health and social problems.

Limitations: The limitations of the study include (1) a reduced sample size because of non-participation of seven general practices; (2) incompleteness and unreliability of some of the Quality and Outcomes Framework data; (3) unavailability of accurate data on intervention intensity and patient comorbidity; (4) reliance on an exploratory analysis with significant sensitivity analysis; and (5) limited perspectives from voluntary, community and social enterprise.

Conclusions: This social prescribing model resulted in a small improvement in glycaemic control. Outcome effects varied across different groups and the experience of social prescribing differed depending on client circumstances.

Future work: To examine how the NHS Primary Care Network social prescribing is being operationalised; its impact on health outcomes, service use and costs; and its tailoring to different contexts.

Trial registration: This trial is registered as ISRCTN13880272.

Funding: This project was funded by the National Institute for Health and Care Research (NIHR) Public Health Research programme, Community Groups and Health Promotion (grant no. 16/122/33) and will be published in full in Public Health Research; Vol. 11, No. 2. See the NIHR Journals Library website for further project information.

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英格兰东北部社会处方干预对成人2型糖尿病的影响:SPRING_NE多方法研究
背景:链接工作者社会处方使保健专业人员能够通过将患者与各种服务联系起来来解决患者的非医疗需求。缺乏证据证明其有效性以及链接工作者和客户如何体验它。目的:评估环节工作者社会处方干预对健康和医疗保健成本和利用的影响和成本,并观察环节工作者的服务和患者参与情况。数据来源:质量结果框架和辅助服务使用数据。设计:采用多种方法,包括:(1)准实验评估社会处方对健康和医疗保健使用的影响,(2)成本效益分析,(3)探索干预措施交付和接收的民族志方法,以及(4)一项补充访谈研究,研究英国首次COVID-19封锁期间(2020年4月至7月)的干预影响。研究人群和环境:居住在英国英格兰东北部一个社会经济贫困地区的40-74岁2型糖尿病患者和相关工作人员。干预措施:将工人社会处方联系起来,以改善长期疾病患者的健康和福祉相关结果。参与者:(1)健康结局研究,约n = 8400例患者;EuroQol-5 Dimensions,五级版本(EQ-5D-5L),研究,n = 694(基线)和n = 474(随访);(2)民族志,n = 20名链接工人和n = 19名客户;和COVID-19访谈,n = 14名员工和n = 44名客户。主要结局指标:主要结局指标为糖化血红蛋白水平(HbA1c;主要结局)、体重指数、血压、胆固醇水平、吸烟状况、医疗保健成本和利用以及EQ-5D-5L评分。结果:对13种干预和11种对照的约8400例患者的意向治疗分析显示,HbA1c水平(-1.11 mmol/mol)的差异具有统计学意义(尽管没有临床意义),高血压的概率降低了1.5个百分点,但对其他结果没有统计学意义。保健费用估计从18.22英镑(有一种额外合并症的个人)到50.35英镑(没有额外合并症的个人)不等。观察到从计划外(非选择性和意外和急诊入院)到计划护理(选择性和门诊护理)的统计上不显著的转变。亚组分析显示,生活在更贫困地区的人、白人和合并症较少的人受益更多。干预本身的平均成本为每位参与者1345英镑;平均健康增量为0.004质量调整生命年(95%可信区间-0.022 ~ 0.029);每增加一个质量调整生命年,增量成本效益比为327,250英镑。人种学数据表明,成功嵌入的全面社会处方提供了支持链接,以导航健康的社会决定因素,这是一项挑战,但可以为改善健康和福祉提供机会。然而,干预是异质的,并以意想不到的方式被交付环境所塑造。促成转诊和实现目标的压力减损了面对面接触和处理有复杂健康和社会问题的人的挫折的能力。局限性:该研究的局限性包括:(1)由于没有参加7个全科医生,样本量减少;(2)一些质量和结果框架数据不完整和不可靠;(3)缺乏干预强度和患者合并症的准确数据;(4)依赖具有显著敏感性分析的探索性分析;(5)来自志愿者、社区和社会企业的有限观点。结论:这种社会处方模式对血糖控制有一定的改善。结果效果在不同的群体中有所不同,社会处方的经验因客户环境而异。未来的工作:检查NHS初级保健网络社会处方是如何运作的;它对健康结果、服务使用和成本的影响;它可以根据不同的情况进行剪裁。试验注册:该试验注册号为ISRCTN13880272。资助:本项目由国家卫生和保健研究所(NIHR)公共卫生研究方案、社区团体和健康促进(批准号:16/122/33),并将全文发表在《公共卫生研究》上;第11卷第2期请参阅NIHR期刊图书馆网站了解更多项目信息。
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