Clinical study on the correlation between monocyte-related ratios and calcification of the abdominal aorta in peritoneal dialysis patients.

IF 1.5 4区医学 Q3 HEMATOLOGY Therapeutic Apheresis and Dialysis Pub Date : 2023-08-01 DOI:10.1111/1744-9987.13978

Jiani Sun, Yuan Lu, Lei Shen, Deyu Xu, Wengang Sha, Ling Zhou, Jianzhong Li

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引用次数: 1

Abstract

Introduction: We aimed to investigate the relationship between monocyte/lymphocyte ratio (MLR) and monocyte/high-density lipoprotein ratio (MHR) with abdominal aortic calcification (AAC) in patients on peritoneal dialysis (PD).

Methods: The time-averaged (TA) of relevant indexes and AAC scores (AACs) of 160 eligible patients were measured.

Results: Patients divided into the new AAC (n = 57) and the other without (n = 82). High TA-MLR (OR = 110.537, p = 0.018) and long duration of dialysis (OR = 1.045, p < 0.001) were independent risk factors of the new AAC. Patients divided into the no AAC (n = 82), the moderate-to-severe AAC (n = 26), and the mild AAC (n = 52). High TA-MLR (OR = 42.649, p = 0.032), high age at starting PD (OR = 1.055, p < 0.001), and long duration of PD (OR = 1.036, p < 0.001) were independent risk factors of AAC severity.

Conclusions: MLR is an independent risk factor for the occurrence and severity of AAC and its value for the assessment of AAC is better than MHR.

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腹膜透析患者单细胞相关比值与腹主动脉钙化相关性的临床研究。

前言:我们旨在探讨腹膜透析(PD)患者腹主动脉钙化(AAC)与单核细胞/淋巴细胞比率(MLR)和单核细胞/高密度脂蛋白比率(MHR)的关系。方法:测定160例患者相关指标的时间平均值(TA)和AAC评分(AACs)。结果:患者分为新发AAC (n = 57)和未发AAC (n = 82)。TA-MLR高(OR = 110.537, p = 0.018)、透析时间长(OR = 1.045, p)结论:MLR是AAC发生及严重程度的独立危险因素，其评价AAC的价值优于MHR。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Therapeutic Apheresis and Dialysis 医学-泌尿学与肾脏学

CiteScore

3.00

自引率

10.50%

发文量

166

审稿时长

6-12 weeks

期刊介绍： Therapeutic Apheresis and Dialysis is the official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis and the Japanese Society for Dialysis Therapy. The Journal publishes original articles, editorial comments, review articles, case reports, meeting abstracts and Communications information on apheresis and dialysis technologies and treatments.