Early Vitrectomy: An Effective Treatment for Acute Postcataract Surgery Endophthalmitis.

Farhad Fazel Najafabadi, Ali Salehi, Mohammad Hadi Vaezi, Heshmatollah Ghanbari, Mohamadreza Fazel Najafabadi, Nima Koosha, Zahra Jafarzadeh
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Abstract

Background: Endophthalmitis is a rare but a high morbid complication after cataract surgery, and a gold standard treatment is not recommended yet. In this study, we aim to evaluate the effect of early vitrectomy on the visual acuity of patients with postcataract endophthalmitis.

Materials and methods: This study was a single-arm clinical trial on 27 patients with postcataract surgery endophthalmitis. Early vitrectomy was the intervention. Visual acuity as the primary outcome was evaluated and compared at baseline, at discharge, and 1 and 3 months after the intervention.

Results: From 27 patients who included in our study, six patients gain favorable visual acuity of 5/10 and above (success rate = 22%), and four of them have no improvement in their visual acuity. Retinal detachment was reported as a complication in just one case. Negative culture was a predictor for success in terms of visual acuity after the surgery. All patients who gain favorable results, presented in the first 15 days after the cataract surgery.

Conclusion: The result of our study showed that, considering complete, early vitrectomy for the treatment of postcataract surgery endophthalmitis, especially for those who presented in the first 15 days of cataract surgery and for those who have negative culture is promising.

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早期玻璃体切除术:急性白内障术后眼内炎的有效治疗方法。
背景:眼内炎是白内障手术后一种罕见但高发病率的并发症,目前尚未推荐黄金标准治疗方法。在本研究中,我们旨在评估早期玻璃体切除术对白内障后眼内炎患者视力的影响。材料与方法:本研究为单臂临床试验,纳入27例白内障术后眼内炎患者。早期玻璃体切除术是干预措施。在基线、出院时以及干预后1个月和3个月对视力作为主要指标进行评估和比较。结果:纳入研究的27例患者中,6例视力达到5/10及以上良好(成功率22%),4例视力无改善。据报道,视网膜脱离仅为一例并发症。阴性培养是术后视力成功的一个预测指标。所有获得良好结果的患者均出现在白内障手术后的前15天。结论:我们的研究结果表明,考虑到完整,早期玻璃体切除术治疗白内障术后眼内炎,特别是对白内障手术前15天出现的患者和培养阴性的患者是有希望的。
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