{"title":"Association of Lymphovascular Space Invasion (LVSI) with Histological Tumor Grade and Myometrial Invasion in Endometrial Carcinoma: A Review Study.","authors":"Azita Rafiee, Fereshteh Mohammadizadeh","doi":"10.4103/abr.abr_52_23","DOIUrl":null,"url":null,"abstract":"<p><p>Endometrial carcinoma is one of the most frequent gynecological cancers in developed countries. Lymphovascular space invasion (LVSI), histological grade, and myometrial invasion (MMI) are important prognostic factors of endometrial carcinoma. LVSI is considered an independent poor prognostic factor in endometrial carcinoma. Based on the importance of LVSI, this study aimed to discuss the association of LVSI with tumor grade and MMI. A search of PubMed, EMBASE, Web of Science, Scopus, Google Scholar, and Cochrane Library was carried out to collect related studies. Consequently, most studies showed that LVSI is significantly associated with higher histologic grade and deep MMI.</p>","PeriodicalId":7225,"journal":{"name":"Advanced Biomedical Research","volume":"12 ","pages":"159"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/26/0d/ABR-12-159.PMC10410422.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Biomedical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/abr.abr_52_23","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Endometrial carcinoma is one of the most frequent gynecological cancers in developed countries. Lymphovascular space invasion (LVSI), histological grade, and myometrial invasion (MMI) are important prognostic factors of endometrial carcinoma. LVSI is considered an independent poor prognostic factor in endometrial carcinoma. Based on the importance of LVSI, this study aimed to discuss the association of LVSI with tumor grade and MMI. A search of PubMed, EMBASE, Web of Science, Scopus, Google Scholar, and Cochrane Library was carried out to collect related studies. Consequently, most studies showed that LVSI is significantly associated with higher histologic grade and deep MMI.
子宫内膜癌是发达国家最常见的妇科肿瘤之一。淋巴血管间隙浸润(LVSI)、组织学分级和子宫肌层浸润(MMI)是影响子宫内膜癌预后的重要因素。LVSI被认为是子宫内膜癌预后不良的独立因素。基于LVSI的重要性，本研究旨在探讨LVSI与肿瘤分级及MMI的关系。检索PubMed、EMBASE、Web of Science、Scopus、Google Scholar和Cochrane Library，收集相关研究。因此，大多数研究表明LVSI与较高的组织学分级和深部MMI显著相关。
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