Tolvaptan治疗后垂体小结节形成患者的抗利尿激素产生不当的复发综合征。

IF 1.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Experimental and Clinical Endocrinology & Diabetes Pub Date : 2023-09-01 Epub Date: 2023-06-26 DOI:10.1055/a-2093-1002
Lennart M Reinke, Anna Katharina Seoudy, Friedericke Gärtner, Nathalie Rohmann, Dominik M Schulte, Stefan Schreiber, Olav Jansen, Matthias Laudes
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引用次数: 0

摘要

ADH分泌不当综合征(SIADH)是低钠水平的常见原因,病因多种多样。在此,我们报告了一例41岁男性患者,该患者被诊断为SIADH,对托伐普坦治疗反应良好。令人感兴趣的是,作为一种潜在的独特原因,磁共振成像显示垂体后叶存在微结节结构,而SIADH的其他常见原因尚无法确定。因此,据我们所知,这是第一例与垂体微结节结构相关的托伐普坦反应性SIADH。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Relapsing Syndrome of Inappropriate Antidiuretic Hormone Production Responding to Tolvaptan Treatment in a Patient With a Micronodular Formation of the Posterior Pituitary Gland.

The syndrome of inappropriate ADH-secretion (SIADH) is a common cause of low sodium levels with diverse aetiology. Here, we report a case of a 41 years old male patient diagnosed with SIADH and a good response to Tolvaptan therapy. Of interest, as a potential unique cause, magnetic resonance imaging revealed a micronodular structure in the posterior pituitary, while no other common cause of SIADH could be identified. Hence, to the best of our knowledge, this is the first case of a Tolvaptan-responsive SIADH associated with a pituitary micronodular structure.

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来源期刊
CiteScore
4.10
自引率
5.60%
发文量
72
审稿时长
3 months
期刊介绍: Publishing outstanding articles from all fields of endocrinology and diabetology, from molecular biology to clinical research, this journal is a brilliant resource. Since being published in English in 1983, the popularity of this journal has grown steadily, reflecting the importance of this publication within its field. Original contributions and short communications appear in each issue along with reviews addressing current topics. In addition, supplementary issues are published each year presenting abstracts or proceedings of national and international scientific meetings. The journal was initially published in German and is still the oldest endocrinological periodical in the German-language market!
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