{"title":"利用基于残差网络的优化深度学习检测脑肿瘤","authors":"Saransh Rohilla, Shruti Jain","doi":"10.2174/1573409920666230816090626","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Diagnosis and treatment planning play a very vital role in improving the survival of oncological patients. However, there is high variability in the shape, size, and structure of the tumor, making automatic segmentation difficult. The automatic and accurate detection and segmentation methods for Brain tumors are proposed in this paper.</p><p><strong>Methods: </strong>A modified ResNet50 model was used for tumor detection, and a ResUNetmodel-based convolutional neural network for segmentation is proposed in this paper. The detection and segmentation were performed on the same dataset consisting of pre-contrast, FLAIR, and postcontrast MRI images of 110 patients collected from the Cancer Imaging Archive. Due to the use of Residual Networks, the authors observed improvement in evaluation parameters, such as accuracy for tumor detection and dice similarity coefficient for tumor segmentation.</p><p><strong>Results: </strong>The accuracy of tumor detection and Dice Similarity Coefficient achieved by the segmentation model were 96.77% and 0.893, respectively, for the TCIA dataset. The results were compared based on manual segmentation and existing segmentation techniques. The tumor mask was also individually compared to the ground truth using the SSIM value. The proposed detection and segmentation models were validated on BraTS2015 and BraTS2017 datasets, and the results were consensus.</p><p><strong>Conclusion: </strong>The use of residual networks in both the detection and the segmentation model resulted in improved accuracy and DSC score. DSC score was increased by 5.9% compared to the UNet model, and the accuracy of the model was increased from 92% to 96.77% for the test set.</p>","PeriodicalId":10886,"journal":{"name":"Current computer-aided drug design","volume":" ","pages":""},"PeriodicalIF":1.5000,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Detection of Brain Tumor Employing Residual Network-based Optimized Deep Learning\",\"authors\":\"Saransh Rohilla, Shruti Jain\",\"doi\":\"10.2174/1573409920666230816090626\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Diagnosis and treatment planning play a very vital role in improving the survival of oncological patients. However, there is high variability in the shape, size, and structure of the tumor, making automatic segmentation difficult. The automatic and accurate detection and segmentation methods for Brain tumors are proposed in this paper.</p><p><strong>Methods: </strong>A modified ResNet50 model was used for tumor detection, and a ResUNetmodel-based convolutional neural network for segmentation is proposed in this paper. The detection and segmentation were performed on the same dataset consisting of pre-contrast, FLAIR, and postcontrast MRI images of 110 patients collected from the Cancer Imaging Archive. Due to the use of Residual Networks, the authors observed improvement in evaluation parameters, such as accuracy for tumor detection and dice similarity coefficient for tumor segmentation.</p><p><strong>Results: </strong>The accuracy of tumor detection and Dice Similarity Coefficient achieved by the segmentation model were 96.77% and 0.893, respectively, for the TCIA dataset. The results were compared based on manual segmentation and existing segmentation techniques. The tumor mask was also individually compared to the ground truth using the SSIM value. The proposed detection and segmentation models were validated on BraTS2015 and BraTS2017 datasets, and the results were consensus.</p><p><strong>Conclusion: </strong>The use of residual networks in both the detection and the segmentation model resulted in improved accuracy and DSC score. DSC score was increased by 5.9% compared to the UNet model, and the accuracy of the model was increased from 92% to 96.77% for the test set.</p>\",\"PeriodicalId\":10886,\"journal\":{\"name\":\"Current computer-aided drug design\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2024-08-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current computer-aided drug design\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2174/1573409920666230816090626\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, MEDICINAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current computer-aided drug design","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2174/1573409920666230816090626","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
Detection of Brain Tumor Employing Residual Network-based Optimized Deep Learning
Background: Diagnosis and treatment planning play a very vital role in improving the survival of oncological patients. However, there is high variability in the shape, size, and structure of the tumor, making automatic segmentation difficult. The automatic and accurate detection and segmentation methods for Brain tumors are proposed in this paper.
Methods: A modified ResNet50 model was used for tumor detection, and a ResUNetmodel-based convolutional neural network for segmentation is proposed in this paper. The detection and segmentation were performed on the same dataset consisting of pre-contrast, FLAIR, and postcontrast MRI images of 110 patients collected from the Cancer Imaging Archive. Due to the use of Residual Networks, the authors observed improvement in evaluation parameters, such as accuracy for tumor detection and dice similarity coefficient for tumor segmentation.
Results: The accuracy of tumor detection and Dice Similarity Coefficient achieved by the segmentation model were 96.77% and 0.893, respectively, for the TCIA dataset. The results were compared based on manual segmentation and existing segmentation techniques. The tumor mask was also individually compared to the ground truth using the SSIM value. The proposed detection and segmentation models were validated on BraTS2015 and BraTS2017 datasets, and the results were consensus.
Conclusion: The use of residual networks in both the detection and the segmentation model resulted in improved accuracy and DSC score. DSC score was increased by 5.9% compared to the UNet model, and the accuracy of the model was increased from 92% to 96.77% for the test set.
期刊介绍:
Aims & Scope
Current Computer-Aided Drug Design aims to publish all the latest developments in drug design based on computational techniques. The field of computer-aided drug design has had extensive impact in the area of drug design.
Current Computer-Aided Drug Design is an essential journal for all medicinal chemists who wish to be kept informed and up-to-date with all the latest and important developments in computer-aided methodologies and their applications in drug discovery. Each issue contains a series of timely, in-depth reviews, original research articles and letter articles written by leaders in the field, covering a range of computational techniques for drug design, screening, ADME studies, theoretical chemistry; computational chemistry; computer and molecular graphics; molecular modeling; protein engineering; drug design; expert systems; general structure-property relationships; molecular dynamics; chemical database development and usage etc., providing excellent rationales for drug development.