冠状病毒病-2019大流行期间住院传染病患者的药物和解服务:一项观察性研究

IF 1.8 Q3 PHARMACOLOGY & PHARMACY Turkish Journal of Pharmaceutical Sciences Pub Date : 2023-08-22 DOI:10.4274/tjps.galenos.2022.08455
Cüneyd Enver, Buket Ertürk Şengel, Mesut Sancar, Volkan Korten, Betul Okuyan
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引用次数: 1

摘要

目的:了解2019冠状病毒病(COVID-19)大流行期间接受临床药师主导的住院感染性疾病患者用药差异的发生率、类型及非故意用药差异的相关因素,确定出院后30 d内再入院率和急诊就诊率。材料与方法:本观察性研究于2020年7月至2021年2月在某三级大学附属医院内科及传染病病房对住院的成人传染病患者进行研究。亲自或电话提供药物调解服务(包括患者咨询)。评估在药物调解服务中发现的药物差异的数量和类型、药师推荐的接受率以及入院时至少有一次非故意药物差异的相关因素。随访时,通过电话评估出院后30天内的再入院和急诊就诊情况。结果:146例患者中,84例(57.5%)在入院时至少有一次非故意差异。在3例出院患者中,仅确定了3个非故意差异。药师对用药差异的建议均被医师接受。患有COVID-19[优势比(OR): 2.25, 95%可信区间(CI): 1.15-4.40;结论:在新冠肺炎疫情期间,通过上门或电话提供药物调解服务,有助于发现和解决非故意用药差异。
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Medication Reconciliation Service in Hospitalized Patients with Infectious Diseases During Coronavirus Disease-2019 Pandemic: An Observational Study.

Objectives: To determine the prevalence and type of medication discrepancies and factors associated with unintentional discrepancies and identify the rate of hospital readmission and emergency service visit within 30 days after discharge among hospitalized patients with infectious diseases and receiving clinical pharmacist-led medication reconciliation during the coronavirus disease-2019 (COVID-19) pandemic.

Materials and methods: This observational study was conducted in the internal medicine and infectious diseases wards of a tertiary university hospital between July 2020 and February 2021 among hospitalized adult patients with infectious diseases. Medication reconciliation service (including patient counseling) was provided in person or by telephone. The number and type of medication discrepancies detected during the medication reconciliation services, the acceptance rate of pharmacists' recommendation, and factors associated with having at least one unintentional medication discrepancy at admission were evaluated. At follow-up, hospital readmission and emergency service visit within 30 days after discharge were assessed by telephone.

Results: Among 146 patients, 84 (57.5%) had at least one unintentional discrepancy at admission. Only three unintentional discrepancies were determined in three patients at hospital discharge. All the pharmacists' recommendations for medication discrepancies were accepted by the physicians. Having COVID-19 [odds ratio (OR): 2.25, 95% confidence interval (CI): 1.15-4.40; p<0.05], being at a high risk for medication error (OR: 2.01, 95% CI: 1.03-3.92; p<0.05), and higher number of medications used at home (OR: 1.41, 95% CI: 1.23-1.61; p<0.001) were associated with having at least one unintentional discrepancy at admission. The rates of 30 day hospital readmission and admission to the emergency medical service were 12.3% and 15.8%, respectively.

Conclusion: Medication reconciliation service provided by in-person or by telephone was useful for detecting and solving unintentional medication discrepancies during the COVID-19 pandemic.

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CiteScore
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自引率
5.90%
发文量
79
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