煤气炉儿童哮喘发作:一个教学机会

Louis Anthony Cox Jr.
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引用次数: 1

摘要

最近的几则新闻报道称,在美国,燃气灶造成的室内空气污染导致了约13%的儿童哮喘,这让许多政客和公众感到震惊。对流行病学风险评估的可重复性和可信度的研究已经确定了一些常见的可疑研究实践(QRP),应该避免这些实践,以从流行病学数据中得出合理的因果结论。此类QRP的例子包括在不使用允许有效因果推断的研究设计或数据分析的情况下声称因果关系;在不考虑研究和目标人群差异的情况下,根据特定人群、时间段和地点的数据将风险估计推广或转移到不同的人群;声称因果关系而不讨论或定量纠正混淆、外部有效性偏差或其他偏差;没有提及或解决矛盾的证据。我们从这些QRP的角度研究了最近估计的燃气炉儿童哮喘的关联,并得出结论,它体现了所有这些关联。关于美国约13%的儿童哮喘可以通过减少暴露于燃气炉污染来预防的定量说法,没有得到收集的数据或用于分析数据的关联度(人口归因分数)的支持。在美国,减少暴露在煤气炉污染中会减轻儿童哮喘负担的定性研究结果没有被证明是有效的。在报告或回应日常暴露对健康造成重大危害的说法之前,系统地检查QRP是如何以及是否得到解决的,这可能会减少基于QRP的感知风险的社会放大,并有助于提高已发表的流行病学风险评估的可信度和可信度。
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The gas stove-childhood asthma kerfuffle: A teaching opportunity

Several recent news stories have alarmed many politicians and members of the public by reporting that indoor air pollution from gas stoves causes about 13% of childhood asthma in the United States. Research on the reproducibility and trustworthiness of epidemiological risk assessments has identified a number of common questionable research practices (QRPs) that should be avoided to draw sound causal conclusions from epidemiological data. Examples of such QRPs include claiming causation without using study designs or data analyses that allow valid causal inferences; generalizing or transporting risk estimates based on data for specific populations, time periods, and locations to different ones without accounting for differences in the study and target populations; claiming causation without discussing or quantitatively correcting for confounding, external validity bias, or other biases; and not mentioning or resolving contradictory evidence. We examine the recently estimated gas stove-childhood asthma associations from the perspective of these QRPs and conclude that it exemplifies all of them. The quantitative claim that about 13% of childhood asthma in the United States could be prevented by reducing exposure to gas stove pollution is not supported by the data collected or by the measures of association (Population Attributable Fractions) used to analyze the data. The qualitative finding that reducing exposure to gas stove pollution would reduce the burden of childhood asthma in the United States has no demonstrated validity. Systematically checking how and whether QRPs have been addressed before reporting or responding to claims that everyday exposures cause substantial harm to health might reduce social amplification of perceived risks based on QRPs and help to improve the credibility and trustworthiness of published epidemiological risk assessments.

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来源期刊
Global Epidemiology
Global Epidemiology Medicine-Infectious Diseases
CiteScore
5.00
自引率
0.00%
发文量
22
审稿时长
39 days
期刊最新文献
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