使用2021年IDF-DAR风险计算器的风险分层和孟加拉国2型糖尿病受试者斋月期间的禁食经历：DAR-BAN研究

IF 4.2 Q1 ENDOCRINOLOGY & METABOLISM Journal of Clinical and Translational Endocrinology Pub Date : 2023-03-01 DOI:10.1016/j.jcte.2023.100315

A.B.M. Kamrul-Hasan , Muhammad Shah Alam , Md. Ahamedul Kabir , Sumon Rahman Chowdhury , Muhammad Abdul Hannan , Emran Ur Rashid Chowdhury , Md. Mainul Ahsan , Choman Abdullah Mohana , Mohammad Hasan Iftekhar , Mohammad Jahid Hasan , Samir Kumar Talukder

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引用次数: 0

摘要

目的根据IDF-DAR 2021指南对2型糖尿病（T2DM）患者进行风险分层，并观察他们对基于风险类别的建议和禁食经验的反应性。方法这项前瞻性研究在2022年斋月期间进行，评估了患有T2DM的成年人，并使用IDF-DAR 2021风险分层工具对他们进行了分类。结果1328名参与者（年龄51.1±11.9岁，女性61.1%）中，只有29.6%的人在斋月前HbA1c<；7.5%。根据IDF-DAR风险类别，低风险（应能禁食）、中风险（不禁食）和高风险（不应禁食）组的参与者频率分别为44.2%、45.7%和10.1%。大多数人（95.5%）打算禁食，71%的人在斋月的30天里禁食。低血糖（3.5%）和高血糖（2.0%）的总频率较低。高风险组的低血糖和高血糖风险分别是低风险组的3.74倍和3.86倍。结论新的IDF-DAR风险评分系统在T2DM患者禁食并发症的风险分类中似乎是保守的。

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Risk stratification using the 2021 IDF-DAR risk calculator and fasting experience of Bangladeshi subjects with type 2 diabetes in Ramadan: The DAR-BAN study

Aims

To risk-stratify patients with type 2 diabetes mellitus (T2DM) according to the IDF-DAR 2021 guidelines and observe their responsiveness to risk-category-based recommendations and fasting experience.

Methods

This prospective study, conducted in the peri-Ramadan period of 2022, evaluated adults with T2DM and categorized them using the IDF-DAR 2021 risk stratification tool. Recommendations for fasting according to the risk categories were made, their intention to fast was recorded, and follow-up data were collected within one month of the end of Ramadan.

Results

Among 1328 participants (age 51.1 ± 11.9 years, female 61.1 %), only 29.6 % had pre-Ramadan HbA1c < 7.5 %. According to the IDF-DAR risk category, the frequencies of participants in the low-risk (should be able to fast), moderate-risk (not to fast), and high-risk (should not fast) groups were 44.2 %, 45.7 %, and 10.1 %, respectively. Most (95.5 %) intended to fast, and 71 % fasted the full 30 days of Ramadan. The overall frequencies of hypoglycemia (3.5 %) and hyperglycemia (2.0 %) were low. Hypoglycemia and hyperglycemia risks were 3.74-fold and 3.86-fold higher in the high-risk group than in the low-risk group.