BioWebEngine:生物信息学研究的生成环境

Paolo Bottoni, T. Castrignanò, Tiziano Flati, Francesco Maggi
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引用次数: 0

摘要

随着大规模平行基因组测序技术的出现,生物信息学进入了“大数据”时代。开发该领域的应用程序需要领域专家与IT专家的合作,以指定能够查询多个来源、以多种格式获取数据、搜索重要模式并根据几种可视化类型呈现获得的结果的程序。基于在开发几个用于访问和查询基因组学和蛋白质组学数据库的Web门户中获得的经验,我们推导了这些门户的元模型,并实现了BioWebEngine,这是一个生成环境,在该环境中,用户可以根据元模型指定和部署预期的门户。
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BioWebEngine: A generation environment for bioinformatics research
With technologies for massively parallel genome sequencing available, bioinformatics has entered the “big data” era. Developing applications in this field involves collaboration of domain experts with IT specialists to specify programs able to query several sources, obtain data in several formats, search them for significant patterns and present the obtained results according to several types of visualisation. Based on the experience gained in developing several Web portals for accessing and querying genomics and proteomics databases, we have derived a meta-model of such portals and implemented BioWebEngine, a generation environment where a user is assisted in specifying and deploying the intended portal according to the meta-model.
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