人类骨骼肌组织核共振谱后处理优化的数学方法概念

E. Hoff, L. Brechtel, G. Barwolff, N. Natho, O. Pfeiffer, S. Jeschke
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引用次数: 0

摘要

通过31P核磁共振(NMR)波谱,可以测量静止和运动(人体)肌肉组织的代谢状况和变化。应用范围从肌病的检查到竞技运动员肌肉纤维成分的分析。利用31P-NMR波谱法获得的大量人体骨骼肌测量数据正在等待处理。由于单个光谱的人工处理需要一个熟练的人工分析仪大约半小时的工作,完成这项工作需要几个人年的工作。在此基础上,提出了对31P- NMR数据进行自动后处理的概念。
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A concept of mathematical methods for the optimization of the post-processing of nuclear resonance spectra of the human skeletal musculature
By means of 31P nuclear magnetic resonance (NMR) spectroscopy, metabolic conditions and changes in the resting and moving (human) musculature can be measured. Applications range from the examination of myopathies to the analysis of the composition of muscle fibers of competitive athletes. A vast amount of measurements of human skeletal muscles acquired using the 31P-NMR spectroscopy is waiting at hand to be processed. As manual processing of a single spectrum requires about half an hour of work form an exercised human analyzer several man-years of work are needed to do the job. Therefore a concept for the automatic post-processing of data acquired by 31P- NMR spectroscopy is presented.
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