格列本脲在高原脑缺血中的胰腺外作用特点

M. Shuvalova, Y. Shidakov, A. Shanazarov, D. Zhanuzakov, A. Mamytova
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引用次数: 0

摘要

本文研究了高原地区脑缺血时脑血管丛和微循环床成分的重构特征,并介绍了格列本脲对这些结构的作用特点。结果表明,高原地区磺酰脲受体1 (sulfonylurea receptor 1, SUR 1)对格列本脲的敏感性高于低山地区。关键词:脑缺血格列本脲高原
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Features of the extrapancreatic action of glibenclamide in cerebral ischemia in the highlands
The features of remodeling of the components of the vascular plexus and the microcirculatory bed of the brain in cerebral ischemia in the highlands are studied, the features of the action of glibenclamide on these structures are presented. It is shown that the sulfonylurea receptor 1 (SUR 1) in the highlands becomes more sensitive to glibenclamide than in the low mountains. Key words: brain, ischemia, glibenclamide, highlands.
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