{"title":"多功能共聚焦和宽视场荧光显微镜研究膜受体动力学","authors":"M. Bathe-Peters, P. Gmach, P. Annibale, M. Lohse","doi":"10.1364/COSI.2019.JW2A.4","DOIUrl":null,"url":null,"abstract":"We present the setup of a fluorescence microscope combining TIRF and confocal microscopy within one body to address multi-scale dynamics of GPCRs on plasma membranes of living cells with adequate spatial and temporal resolution.","PeriodicalId":123636,"journal":{"name":"Imaging and Applied Optics 2019 (COSI, IS, MATH, pcAOP)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"All-in-one confocal and widefield fluorescence microscope to investigate membrane receptor dynamics\",\"authors\":\"M. Bathe-Peters, P. Gmach, P. Annibale, M. Lohse\",\"doi\":\"10.1364/COSI.2019.JW2A.4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We present the setup of a fluorescence microscope combining TIRF and confocal microscopy within one body to address multi-scale dynamics of GPCRs on plasma membranes of living cells with adequate spatial and temporal resolution.\",\"PeriodicalId\":123636,\"journal\":{\"name\":\"Imaging and Applied Optics 2019 (COSI, IS, MATH, pcAOP)\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-06-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Imaging and Applied Optics 2019 (COSI, IS, MATH, pcAOP)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1364/COSI.2019.JW2A.4\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Imaging and Applied Optics 2019 (COSI, IS, MATH, pcAOP)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1364/COSI.2019.JW2A.4","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
All-in-one confocal and widefield fluorescence microscope to investigate membrane receptor dynamics
We present the setup of a fluorescence microscope combining TIRF and confocal microscopy within one body to address multi-scale dynamics of GPCRs on plasma membranes of living cells with adequate spatial and temporal resolution.