A continuous-flow concentrator based on ion concentration polarization

In this paper, we present a novel and simple method to fabricate a continuous-flow concentrator based on ion concentration polarization phenomenon (ICP). With the capillary force, the Nafion solution can fill the Nafion resin channels, and nanoporous junctions were created to generate ICP. To demonstrate the concentration ability of the device, we conducted the experiments with Rhodamine 6G (positively charged) and fluorescein sodium (negatively charged). As a result, the device is more appropriate to concentrate the negatively charged species with concentration up to 2-fold. For further application, the method is convenient and simple to achieve a high-throughput concentration flow and a higher preconcentration factor.