P54 Combined exposure to vapors, gases, dusts, fumes and tobacco smoke increases the risk of asthma symptoms

P55 Figure 1 Poster sessions A96 Thorax 2021;76(Suppl 2):A1–A205 on N ovem er 1, 2021 by gest. P rocted by coright. httphorax.bm jcom / T hrax: frst pulished as 10.113orax-2021-B T S abscts.165 on 8 N ovem er 221. D ow nladed fom major comorbidity=204 (37), median%predicted FEV1=80 (58–96). The most frequently identified occupations were: office administrator=48 (10), nurse=43 (9), care assistant (personal or institutional) =34 (7), teacher=21 (4), teaching assistant=18 (4). Using OASJEM 186/504 (37) patients may be exposed to 1 respiratory sensitizer or airway irritant, and 140/504 (28) to both categories. Physical demand of work was categorised as follows: sedentary=186/504 (37), light=220 (44), medium=88 (17), heavy=10 (2). Patients employed in medium or heavy physical work had median% FEV1/FVC=66 (52–79), median%predicted FEV1=75 (50–96), and median ACQ7score=2.9 (2.0–3.7). Conclusion Clinicians should enquire about, and exclude, work-related inhalational exposures that may cause or exacerbate symptoms in patients with severe asthma. Clinicians should also be aware of unrecognized work disability, since many patients are employed in physically demanding roles, despite the presence of airflow obstruction and poor asthma control. REFERENCES 1. Le Moual N, et al. Occup Environ Med. 2018;75(7):507–14. 2. Miller AR, et al. Work, Jobs, and Occupations: A Critical Review of the Dictionary of Occupational Titles. Washington DC: National Academy Press, 1980. Cough: is it a problem and what can we do about it? P56 CHRONIC COUGH IN GERMANY: PREVALENCE AND PATIENT CHARACTERISTICS JC Virchow, E Fonseca, H Salmen, VW Li, A Martin, JE Brady, J Schelfhout. University of Rostock Medical Clinic, Rostock, Germany; Merck and Co., Inc., Kenilworth, USA; MSD Sharp and Dohme GmbH, Haar, Germany; Kantar Health Co., Inc., New York,