Pub Date : 2021-11-01DOI: 10.1136/thorax-2021-btsabstracts.157
ER Bradley, HJ Petty, L. Tomlinson, SJ Paterson, S. Brij, BD Al-Sheklly, W. Khan
{"title":"P47 A pilot study for an asthma in pregnancy service within a UK tertiary centre","authors":"ER Bradley, HJ Petty, L. Tomlinson, SJ Paterson, S. Brij, BD Al-Sheklly, W. Khan","doi":"10.1136/thorax-2021-btsabstracts.157","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.157","url":null,"abstract":"","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125229324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-01DOI: 10.1136/thorax-2021-btsabstracts.152
N. Stewart-Kelcher, A. Patel, S. Rahman, A. Hearn, C. Roxas, L. Green, L. Thomson, M. Fernandes, A. Nanzer, D. Jackson, J. Dhariwal, G. d'Ancona
{"title":"P42 Asthma treatment adherence checks: present and future","authors":"N. Stewart-Kelcher, A. Patel, S. Rahman, A. Hearn, C. Roxas, L. Green, L. Thomson, M. Fernandes, A. Nanzer, D. Jackson, J. Dhariwal, G. d'Ancona","doi":"10.1136/thorax-2021-btsabstracts.152","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.152","url":null,"abstract":"","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124094326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-01DOI: 10.1136/thorax-2021-btsabstracts.160
H. Ricketts, R. Chaudhuri, F. Steffensen, J. Baker, D. Buchan, D. Cowan
Background: Patients with asthma may find it impacts their ability to be physically active. Physical activity (PA) has been demonstrated to be lower in asthmatics compared to healthy controls. Obesity is commonly linked with difficult-to-control asthma and can worsen outcomes. At least 150 minutes of moderate physical activity (PA) per week is recommended for all adults by the World Health Organisation. We aimed to compare PA levels in patients with difficult-to-control asthma and body mass index (BMI) ≥25 kg/m 2 (DOW group) and two control groups with mild-moderate asthma, one with BMI <25 kg/ m 2 (MHW group) and one with BMI ≥25 kg/m 2 (MOW group). Methods: This cross-sectional study used 7-day recordings from wrist-worn accelerometers to compare PA between groups. We recorded inactive time, light (LPA) and moderate-vigorous physical activity (MVPA). We also measured novel metrics: intensity gradient (IG) reflecting PA intensity, and average acceleration (AA) reflecting PA volume. Parameters were compared across groups using ANOVA testing for normally distributed data and Kruskall-Wallis for skewed data. Correlation analysis explored associations between PA parameters and asthma measures. As AA was most closely correlated with asthma measures, we compared the highest and lowest AA quartiles using unpaired t and Mann-Whitney U tests, depending on normality. Results: 75 participants were recruited, 25 per group. Inactive time was significantly higher (p<0.001), and LPA (p=0.007), MVPA (p<0.001), IG (p=0.0001) and AA (p<0.0001) all significantly lower in DOW group compared to MHW and MOW groups, even after adjusting for age and BMI. For AA, notable correlations included beclometasone diproprionate-equivalent dose of inhaled corticosteroid (r=-0.591, p<0.0001),
{"title":"P50 Use of accelerometers to compare physical activity levels in participants with asthma grouped by body mass index and asthma severity","authors":"H. Ricketts, R. Chaudhuri, F. Steffensen, J. Baker, D. Buchan, D. Cowan","doi":"10.1136/thorax-2021-btsabstracts.160","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.160","url":null,"abstract":"Background: Patients with asthma may find it impacts their ability to be physically active. Physical activity (PA) has been demonstrated to be lower in asthmatics compared to healthy controls. Obesity is commonly linked with difficult-to-control asthma and can worsen outcomes. At least 150 minutes of moderate physical activity (PA) per week is recommended for all adults by the World Health Organisation. We aimed to compare PA levels in patients with difficult-to-control asthma and body mass index (BMI) ≥25 kg/m 2 (DOW group) and two control groups with mild-moderate asthma, one with BMI <25 kg/ m 2 (MHW group) and one with BMI ≥25 kg/m 2 (MOW group). Methods: This cross-sectional study used 7-day recordings from wrist-worn accelerometers to compare PA between groups. We recorded inactive time, light (LPA) and moderate-vigorous physical activity (MVPA). We also measured novel metrics: intensity gradient (IG) reflecting PA intensity, and average acceleration (AA) reflecting PA volume. Parameters were compared across groups using ANOVA testing for normally distributed data and Kruskall-Wallis for skewed data. Correlation analysis explored associations between PA parameters and asthma measures. As AA was most closely correlated with asthma measures, we compared the highest and lowest AA quartiles using unpaired t and Mann-Whitney U tests, depending on normality. Results: 75 participants were recruited, 25 per group. Inactive time was significantly higher (p<0.001), and LPA (p=0.007), MVPA (p<0.001), IG (p=0.0001) and AA (p<0.0001) all significantly lower in DOW group compared to MHW and MOW groups, even after adjusting for age and BMI. For AA, notable correlations included beclometasone diproprionate-equivalent dose of inhaled corticosteroid (r=-0.591, p<0.0001),","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121727242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-01DOI: 10.1136/thorax-2021-btsabstracts.161
C. Slinger, R. Slinger, K. Prior, A. Vyas, P. Mannion
P51 Table 1 Patient characistics according to diagnosis Poster sessions A94 Thorax 2021;76(Suppl 2):A1–A205 on N ovem er 2, 2021 by gest. P rocted by coright. httphorax.bm jcom / T hrax: frst pulished as 10.113orax-2021-B T S abscts.161 on 8 N ovem er 221. D ow nladed fom
P51表1根据诊断的患者特征海报会议A94胸2021;76(补充2):A1-A205在N月2日，2021年最大。P由赖特保护。httphorax。[jj.com / thrax]首次发表为10.113orax-2021-B T S选集。在8n上的161比上221。我们从
{"title":"P51 Spot the difference? Comparison of clinical characteristics of patients with inducible laryngeal obstruction (ILO) and asthma referred to a severe asthma and airways tertiary centre","authors":"C. Slinger, R. Slinger, K. Prior, A. Vyas, P. Mannion","doi":"10.1136/thorax-2021-btsabstracts.161","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.161","url":null,"abstract":"P51 Table 1 Patient characistics according to diagnosis Poster sessions A94 Thorax 2021;76(Suppl 2):A1–A205 on N ovem er 2, 2021 by gest. P rocted by coright. httphorax.bm jcom / T hrax: frst pulished as 10.113orax-2021-B T S abscts.161 on 8 N ovem er 221. D ow nladed fom","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128465839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-01DOI: 10.1136/thorax-2021-btsabstracts.153
ZK Yusuf, D. Wensley, H. Owton, SJ Singh, Jacquelyn Allen-Collinson
{"title":"P43 Experiences of asthma in the UK-resident adult South Asian population: a qualitative study","authors":"ZK Yusuf, D. Wensley, H. Owton, SJ Singh, Jacquelyn Allen-Collinson","doi":"10.1136/thorax-2021-btsabstracts.153","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.153","url":null,"abstract":"","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134011637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-01DOI: 10.1136/thorax-2021-btsabstracts.165
G. Walters, F. Rezai, N. Le Moual, J. Marsh, A. Bahron, M. Krishna, A. Mansur
{"title":"P55 Occupations, workplace exposures and physical demands of work in patients with severe asthma","authors":"G. Walters, F. Rezai, N. Le Moual, J. Marsh, A. Bahron, M. Krishna, A. Mansur","doi":"10.1136/thorax-2021-btsabstracts.165","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.165","url":null,"abstract":"","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132447885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-01DOI: 10.1136/thorax-2021-btsabstracts.155
G. Walters, J. Marsh, A. Bahron, M. Krishna, A. Mansur
{"title":"P45 Associations between employment and socio-demographic and health-related factors, in patients with severe asthma","authors":"G. Walters, J. Marsh, A. Bahron, M. Krishna, A. Mansur","doi":"10.1136/thorax-2021-btsabstracts.155","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.155","url":null,"abstract":"","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129503779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-01DOI: 10.1136/thorax-2021-btsabstracts.158
I. Pavord, M. Wechsler, L. Ford, J. Maspero, D. Langton, C. Domingo, A. Papi, A. Bourdin, H. Watz, X. Mao, N. Amin, M. Hardin, Y. Zhang, Ah Khan
{"title":"P48 Long-term efficacy of dupilumab in patients with moderate-to-severe asthma in the LIBERTY ASTHMA TRAVERSE open-label extension study: improvements in asthma control and health-related quality of life","authors":"I. Pavord, M. Wechsler, L. Ford, J. Maspero, D. Langton, C. Domingo, A. Papi, A. Bourdin, H. Watz, X. Mao, N. Amin, M. Hardin, Y. Zhang, Ah Khan","doi":"10.1136/thorax-2021-btsabstracts.158","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.158","url":null,"abstract":"","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130225841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-01DOI: 10.1136/thorax-2021-btsabstracts.164
H. Hisinger-Molkanen, P. Pallasaho, A. Sovijarvi, L. Tuomisto, H. Andersén, A. Lindqvist, H. Backman, A. Langhammer, E. Ronmark, B. Lundback, P. Ilmarinen, H. Kankaanranta, P. Piirila
P55 Figure 1 Poster sessions A96 Thorax 2021;76(Suppl 2):A1–A205 on N ovem er 1, 2021 by gest. P rocted by coright. httphorax.bm jcom / T hrax: frst pulished as 10.113orax-2021-B T S abscts.165 on 8 N ovem er 221. D ow nladed fom major comorbidity=204 (37), median%predicted FEV1=80 (58–96). The most frequently identified occupations were: office administrator=48 (10), nurse=43 (9), care assistant (personal or institutional) =34 (7), teacher=21 (4), teaching assistant=18 (4). Using OASJEM 186/504 (37) patients may be exposed to 1 respiratory sensitizer or airway irritant, and 140/504 (28) to both categories. Physical demand of work was categorised as follows: sedentary=186/504 (37), light=220 (44), medium=88 (17), heavy=10 (2). Patients employed in medium or heavy physical work had median% FEV1/FVC=66 (52–79), median%predicted FEV1=75 (50–96), and median ACQ7score=2.9 (2.0–3.7). Conclusion Clinicians should enquire about, and exclude, work-related inhalational exposures that may cause or exacerbate symptoms in patients with severe asthma. Clinicians should also be aware of unrecognized work disability, since many patients are employed in physically demanding roles, despite the presence of airflow obstruction and poor asthma control. REFERENCES 1. Le Moual N, et al. Occup Environ Med. 2018;75(7):507–14. 2. Miller AR, et al. Work, Jobs, and Occupations: A Critical Review of the Dictionary of Occupational Titles. Washington DC: National Academy Press, 1980. Cough: is it a problem and what can we do about it? P56 CHRONIC COUGH IN GERMANY: PREVALENCE AND PATIENT CHARACTERISTICS JC Virchow, E Fonseca, H Salmen, VW Li, A Martin, JE Brady, J Schelfhout. University of Rostock Medical Clinic, Rostock, Germany; Merck and Co., Inc., Kenilworth, USA; MSD Sharp and Dohme GmbH, Haar, Germany; Kantar Health Co., Inc., New York,
P55图1海报会议A96胸腔2021;76(增刊2):A1-A205在N月1日，2021年最大。P由赖特保护。httphorax。[jj.com / thrax]首次发表为10.113orax-2021-B T S选集。在8n上165，在8n上221。主要合并症导致的死亡率为204(37)，预测FEV1的中位数%为80(58-96)。最常见的职业是:办公室管理员=48(10)，护士=43(9)，护理助理(个人或机构)=34(7)，教师=21(4)，教学助理=18(4)。使用OASJEM 186/504(37)患者可能暴露于1种呼吸致敏剂或气道刺激物，140/504(28)患者可能暴露于两类。体力劳动需求分类如下:久坐=186/504(37)，轻度=220(44)，中度=88(17)，重度=10(2)。从事中度或重度体力劳动的患者FEV1/FVC的中位数% =66(52-79)，预测FEV1的中位数% =75 (50-96)，acq7评分中位数=2.9(2.0-3.7)。结论:临床医生应询问并排除可能导致或加重严重哮喘患者症状的与工作相关的吸入性暴露。临床医生还应该意识到未被认识到的工作残疾，因为许多患者从事体力要求高的工作，尽管存在气流阻塞和哮喘控制不良。引用1。Le Moual N，等。中国生物医学工程学报，2018,31(7):557 - 557。2. Miller AR，等。工作，工作和职业:对职业名称词典的批判性评论。华盛顿特区:国家科学院出版社，1980。咳嗽:这是个问题吗?我们能做些什么?[56]陈建军，陈建军，陈建军，陈建军。慢性咳嗽在德国的流行及患者特征。罗斯托克大学医学诊所，罗斯托克，德国;Merck and Co.， Inc.， Kenilworth, USA;德国哈尔的MSD Sharp and Dohme GmbH;纽约Kantar健康有限公司
{"title":"P54 Combined exposure to vapors, gases, dusts, fumes and tobacco smoke increases the risk of asthma symptoms","authors":"H. Hisinger-Molkanen, P. Pallasaho, A. Sovijarvi, L. Tuomisto, H. Andersén, A. Lindqvist, H. Backman, A. Langhammer, E. Ronmark, B. Lundback, P. Ilmarinen, H. Kankaanranta, P. Piirila","doi":"10.1136/thorax-2021-btsabstracts.164","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.164","url":null,"abstract":"P55 Figure 1 Poster sessions A96 Thorax 2021;76(Suppl 2):A1–A205 on N ovem er 1, 2021 by gest. P rocted by coright. httphorax.bm jcom / T hrax: frst pulished as 10.113orax-2021-B T S abscts.165 on 8 N ovem er 221. D ow nladed fom major comorbidity=204 (37), median%predicted FEV1=80 (58–96). The most frequently identified occupations were: office administrator=48 (10), nurse=43 (9), care assistant (personal or institutional) =34 (7), teacher=21 (4), teaching assistant=18 (4). Using OASJEM 186/504 (37) patients may be exposed to 1 respiratory sensitizer or airway irritant, and 140/504 (28) to both categories. Physical demand of work was categorised as follows: sedentary=186/504 (37), light=220 (44), medium=88 (17), heavy=10 (2). Patients employed in medium or heavy physical work had median% FEV1/FVC=66 (52–79), median%predicted FEV1=75 (50–96), and median ACQ7score=2.9 (2.0–3.7). Conclusion Clinicians should enquire about, and exclude, work-related inhalational exposures that may cause or exacerbate symptoms in patients with severe asthma. Clinicians should also be aware of unrecognized work disability, since many patients are employed in physically demanding roles, despite the presence of airflow obstruction and poor asthma control. REFERENCES 1. Le Moual N, et al. Occup Environ Med. 2018;75(7):507–14. 2. Miller AR, et al. Work, Jobs, and Occupations: A Critical Review of the Dictionary of Occupational Titles. Washington DC: National Academy Press, 1980. Cough: is it a problem and what can we do about it? P56 CHRONIC COUGH IN GERMANY: PREVALENCE AND PATIENT CHARACTERISTICS JC Virchow, E Fonseca, H Salmen, VW Li, A Martin, JE Brady, J Schelfhout. University of Rostock Medical Clinic, Rostock, Germany; Merck and Co., Inc., Kenilworth, USA; MSD Sharp and Dohme GmbH, Haar, Germany; Kantar Health Co., Inc., New York,","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"404 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115992428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-01DOI: 10.1136/thorax-2021-btsabstracts.162
J. Haines, J. Wingfield Digby, J. King, J. Smith, S. Fowler
{"title":"P52 A systematic review of the effectiveness of existing non-pharmacological interventions used to treat adults with inducible laryngeal obstruction","authors":"J. Haines, J. Wingfield Digby, J. King, J. Smith, S. Fowler","doi":"10.1136/thorax-2021-btsabstracts.162","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.162","url":null,"abstract":"","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125415006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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