2,4-二硝基苯酚作为二恶英模型化合物的环境免疫传感器检测

Jong-Won Park, S. Kurosawa, Dae-Sang Han, H. Aizawa, Minoru Yoshimoto, Chikashi Nakamura, Jun Miyake, Z. Chang
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引用次数: 4

摘要

我们利用抗二硝基酚抗体固定化石英晶体微天平(QCM)检测二恶英模型化合物2,4-二硝基酚(DNP)与DNP偶联白蛋白之间的竞争反应。该方法在0.01 ~ 100 ng/mL的DNP浓度范围内均可检测到,在1 ~ 100 ng/mL的DNP浓度范围内呈线性相关。
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Environmental immunosensor detection for 2,4-dinitrophenol as a model compound of dioxin
We present the detection of 2,4-dinitrophenol (DNP) as a model compound of dioxin to use the competitive reaction between DNP and DNP-conjugated albumin via anti-DNP antibody immobilized quartz crystal microbalance (QCM). The present QCM method is detectable in the range 0.01 to 100 ng/mL of DNP concentration, and linear correlation is obtained from 1 to 100 ng/mL of DNP concentration.
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