使用卷积神经网络深度学习检测社交媒体上药物-药物相互作用(DDI)

Kelechi Iwuorie, Sabah Mohammed
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引用次数: 0

摘要

药物-药物相互作用(DDI)检测对于药品制造商、药品监管机构和医疗专业人员来说都是一个具有挑战性的问题。进行试验或了解涉及整个人群的每一个病例是不可能的。社交媒体数据的使用研究目前正在获得关注,并且随着机器学习技术的应用已经成功地应用于商业中。本文提出了一种利用卷积神经网络分类器从生物医学文本中提取DDI的方案。该分类器在SemEval 2013 DDIExtraction挑战数据集上进行训练,旨在自动学习给定任务输入的最佳特征表示。已经提出了不同的模型,这些模型利用位置嵌入和在机器学习模型上训练的词嵌入相结合来学习特征。词嵌入对于提供可以训练的词的密集向量表示是必要的,但是训练一个有效的词的向量表示需要大量的数据。为了弥补数据的不足,CNN模型在预训练的PubMed词嵌入上进行训练,该词嵌入为每个词的表示提供了一个大小为200的向量维。该项目旨在提供一个经过训练的CNN模型,其中单词的向量表示由经过训练的权重提供,用于医学文本分类目的。
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Detecting Drug-Drug Interaction (DDI) over the Social Media using Convolution Neural Network Deep Learning
Drug-Drug Interaction (DDI) detection is a challenging problem for drug manufacturers, drug regulatory authorities, and medical professionals alike. It is impossible to run trials or be aware of every single case involving an entire population. Research in the use of social media data is currently gaining attention, and with the application of machine learning techniques has been successfully applied in businesses. This paper presents a project extracting DDI from biomedical text using a Convolutional Neural Network (CNN) classifier. The classifier is trained on the SemEval 2013 DDIExtraction challenge dataset and aims to automatically learn the best feature representation on the input of the given task. Different models have been proposed, which make use of position embeddings in combination with word embeddings trained on the machine learning model to learn features. Word embeddings are necessary for providing dense vector representation of words that can be trained, but a large amount of data is required to train an effective vector representation of words. To compensate for the lack shortage of data, the CNN model is trained on a pre-trained PubMed word embedding, which provides a vector dimension of size 200 for the representation of each word. This project aims to provide a trained CNN model for which vector representation of words is provided by weights that have been trained for medical text classification purposes.
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