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Detecting Drug-Drug Interaction (DDI) over the Social Media using Convolution Neural Network Deep Learning 使用卷积神经网络深度学习检测社交媒体上药物-药物相互作用(DDI)
Pub Date : 2020-08-30 DOI: 10.21742/AJNNIA.2020.4.1.01
Kelechi Iwuorie, Sabah Mohammed
Drug-Drug Interaction (DDI) detection is a challenging problem for drug manufacturers, drug regulatory authorities, and medical professionals alike. It is impossible to run trials or be aware of every single case involving an entire population. Research in the use of social media data is currently gaining attention, and with the application of machine learning techniques has been successfully applied in businesses. This paper presents a project extracting DDI from biomedical text using a Convolutional Neural Network (CNN) classifier. The classifier is trained on the SemEval 2013 DDIExtraction challenge dataset and aims to automatically learn the best feature representation on the input of the given task. Different models have been proposed, which make use of position embeddings in combination with word embeddings trained on the machine learning model to learn features. Word embeddings are necessary for providing dense vector representation of words that can be trained, but a large amount of data is required to train an effective vector representation of words. To compensate for the lack shortage of data, the CNN model is trained on a pre-trained PubMed word embedding, which provides a vector dimension of size 200 for the representation of each word. This project aims to provide a trained CNN model for which vector representation of words is provided by weights that have been trained for medical text classification purposes.
药物-药物相互作用(DDI)检测对于药品制造商、药品监管机构和医疗专业人员来说都是一个具有挑战性的问题。进行试验或了解涉及整个人群的每一个病例是不可能的。社交媒体数据的使用研究目前正在获得关注,并且随着机器学习技术的应用已经成功地应用于商业中。本文提出了一种利用卷积神经网络分类器从生物医学文本中提取DDI的方案。该分类器在SemEval 2013 DDIExtraction挑战数据集上进行训练,旨在自动学习给定任务输入的最佳特征表示。已经提出了不同的模型,这些模型利用位置嵌入和在机器学习模型上训练的词嵌入相结合来学习特征。词嵌入对于提供可以训练的词的密集向量表示是必要的,但是训练一个有效的词的向量表示需要大量的数据。为了弥补数据的不足,CNN模型在预训练的PubMed词嵌入上进行训练,该词嵌入为每个词的表示提供了一个大小为200的向量维。该项目旨在提供一个经过训练的CNN模型,其中单词的向量表示由经过训练的权重提供,用于医学文本分类目的。
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引用次数: 0
A Study on Backpropagation in Artificial Neural Networks 人工神经网络的反向传播研究
Pub Date : 2020-08-30 DOI: 10.21742/AJNNIA.2020.4.1.03
C. Sekhar, P. Meghana
Innovation assumes essential job nowadays in human life to limit the manual work. Execution and exactness with innovation will be high. The Backpropagation neural framework is multilayered, feedforward neural framework and is by a full edge the most extensively utilized. It is moreover seen as one of the least demanding and most wide systems used for managed planning of multilayered neural systems. Backpropagation works by approximating the non-direct association between the data and the yield by changing the weight regards inside. It can furthermore be summarized for the data that is rejected from the planning structures (perceptive limits).
创新在当今人类生活中扮演着重要的角色,以限制体力劳动。执行力和准确性与创新将是很高的。反向传播神经框架是多层前馈神经框架,是目前应用最广泛的一种。此外,它被认为是用于多层神经系统管理规划的要求最低和最广泛的系统之一。反向传播的工作原理是通过改变内部的权重来近似数据和产量之间的非直接关联。它还可以进一步总结为从规划结构中拒绝的数据(感知限制)。
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引用次数: 4
Descriptive Study on the Influence of Intermediation Methods Using Robots on the Improvement of Upper Extremity in Stroke Patients 机器人中介方法对脑卒中患者上肢改善影响的描述性研究
Pub Date : 2020-08-30 DOI: 10.21742/AJNNIA.2020.4.1.02
Youn-bum Sung, Dae-hwan Lee, Jung-Ho Lee
Upper extremity dysfunction, which occurs after stroke, acts as a major cause of obstruction of motion, such as elaborate hand gestures, manipulation, eating, writing, personal hygiene control, expression of opinion, walking and balancing, etc., thus hindering the social independence of patients and causing poor quality of life. Restoration of upper limb function in stroke patients can be said to be important in maintaining the most basic human life. The walking function of the lower extremities is as important as the walking function of the lower extremities in carrying out daily life. In this study, when patient-centered robot assisted rehabilitation was applied to patients with subacute stroke through setting demands and goals for daily life, and motion analysis, it was positive not only to improve the patient’s upper body function, but also to improve the performance of daily activities rather than robot-centered robot assisted rehabilitation with the focus of existing robot devices. In addition, patient-centered robot assisted rehabilitation and robot-centered robotic rehabilitation were more effective than traditional rehabilitation in the range of joint operation of the upper distal region, grip of the hand, and grip strength. On the other hand, patient-centered robot assisted rehabilitation and traditional rehabilitation showed more positive effects than robot-centered robot assisted rehabilitation. Based on these findings, it is meaningful that the research provided a basis for applying patient-centered robotic rehabilitation to improve upper limb function and performance of daily operations in subacute stroke patients. Abstract data (average age, the number of patients in experiment and control groups, the average change score for motor recovery and function level measurements, and the standard deviation of experiment and control groups in criteria) were entered into Excel for Windows. For all the resulting variables, the threshold for rejecting the H 0 hypothesis was set to P < 0.05 (2-tailed)
中风后出现的上肢功能障碍是妨碍患者精细的手势、操作、饮食、写作、个人卫生控制、表达意见、行走、平衡等活动的主要原因,从而阻碍了患者的社会独立,导致生活质量下降。脑卒中患者上肢功能的恢复可以说是维持人类最基本生活的重要因素。在日常生活中,下肢的行走功能与下肢的行走功能同样重要。本研究将以患者为中心的机器人辅助康复应用于亚急性脑卒中患者,通过设定日常生活需求和目标,并进行运动分析,不仅可以改善患者的上半身功能,而且可以改善日常活动的表现,而不是以现有的机器人设备为重点,以机器人为中心的机器人辅助康复。此外,以患者为中心的机器人辅助康复和以机器人为中心的机器人康复在上远端关节操作范围、手部握力和握力方面都比传统康复更有效。另一方面,以患者为中心的机器人辅助康复和传统康复比以机器人为中心的机器人辅助康复效果更好。基于这些发现,本研究为应用以患者为中心的机器人康复改善亚急性脑卒中患者上肢功能和日常操作能力提供了依据,具有重要意义。摘要数据(平均年龄、实验组和对照组患者人数、运动恢复和功能水平测量的平均变化评分、标准中实验组和对照组的标准差)输入Excel for Windows。对于所有结果变量,拒绝h0假设的阈值设为P < 0.05(双尾)。
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引用次数: 0
Machine Learning Algorithms for Parkinson's Disease Detection 帕金森病检测的机器学习算法
Pub Date : 2020-08-30 DOI: 10.21742/AJNNIA.2020.4.1.04
C. Sekhar, M. S. Rao, D. Bhattacharyya
Machine learning now days plays a crucial role in real-time problem analysis and providing solutions with its popular algorithms. Nowadays, in the health care sector, machine learning algorithms are involved in detecting the health issues of patients. This paper elaborated detailed information about how the ML algorithms are detecting Parkinson’s disease. Parkinson’s sickness is caused by the interruption of the brain cells that generate an essence to permit synapses to speak with one another, called dopamine. The cells with the purpose of produce dopamine in the cerebrum are answerable for the control, adjustment and familiarity of developments. At the point when 60-80%of, these cells are missing, at that point adequate dopamine isn’t delivered, and Parkinson’s engine indications show up Here we used random forest and XGBoost algorithms to detect the disease XGBoost giving the best performance than the Random forest.
如今,机器学习在实时问题分析和使用其流行算法提供解决方案方面发挥着至关重要的作用。如今,在医疗保健领域,机器学习算法被用于检测患者的健康问题。本文详细阐述了机器学习算法是如何检测帕金森病的。帕金森氏症是由于脑细胞产生一种叫做多巴胺的物质而中断而引起的,这种物质使突触能够相互交流。大脑中以产生多巴胺为目的的细胞负责控制、调节和熟悉发展。当60-80%的细胞缺失时,多巴胺就无法传递,帕金森氏症就出现了这里我们使用随机森林和XGBoost算法来检测疾病XGBoost比随机森林表现最好。
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引用次数: 1
Utilization of Deep Learning Models in Medical Industries 深度学习模型在医疗行业中的应用
Pub Date : 2019-11-30 DOI: 10.21742/ajnnia.2019.3.1.02
N. Thirupathi Rao
Deep learning is the rapidly growing technology in the field of almost all recent technologies in the market. With the successful application of deep learning in almost all the recent technologies, the growth in all the areas was splendid. The growth in those areas has crossed the expectations of the scientists. Recently, the application of deep learning in the areas of medicine and pharma is growing in recent times in a rapid fast. In the current paper, the authors represent the seven applications or areas in the field of medicine and pharma where the applications of deep learning were implementing and good results are obtaining.
深度学习是市场上几乎所有最新技术领域中发展最快的技术。随着深度学习在几乎所有最新技术中的成功应用,所有领域的增长都是辉煌的。这些领域的增长超出了科学家们的预期。近年来,深度学习在医学和制药领域的应用正在迅速发展。在本文中,作者代表了医学和制药领域的七个应用或领域,这些应用正在实施深度学习并取得了良好的效果。
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引用次数: 0
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Asia-Pacific Journal of Neural Networks and Its Applications
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