Organic electrochemical transistors for biosensing

Conjugated polymers provide a unique toolbox for establishing electrical communication with biological systems. In the first half of this talk, I will introduce the type of conjugated polymers used at the biological interface. I will then show how we designed organic electrochemical transistors (OECTs) for protein detection at the physical limit and challenged them using COVID-19 patient samples, marking a considerable step toward biochemical sensing. I will discuss that advances in bioelectronic device designs do not appear by chance but stem from in-depth investigations of the active materials' transport properties, understanding of device operation, and enhancing materials’ compatibility with biorecognition units.