基于个体的细菌生物膜模型的矩近似应用

M. J.D., C. F., M. N., D. G.
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引用次数: 1

摘要

我们考虑了一个基于个体的二维生物膜模型,其中细菌可以产生聚合物物质(EPS),聚合物生成与细菌之间的耦合创造了各种生物膜结构。然后,我们推导了细菌和EPS颗粒大小的一阶和二阶矩演化方程。这种动态的近似计算比整个IBM的计算要轻得多,因此更系统的探索更容易,特别是在大型细菌种群的情况下。我们表明,第二矩近似准确地预测了细菌和聚合物的数量。并给出了其空间分布的相关信息。
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Applying a Moment Approximation to a Bacterial Biofilm Individual-Based Model
We consider a 2D individual-based model of biofilm, in which bacteria can generate a polymeric substance (EPS), The coupling between polymer generation and bacteria creates a variety of biofilm structures. Then, we derive the equations of first and second moment evolution for the bacteria and EPS particle population sizes. This approximation of the dynamics is much lighter to compute than the whole IBM, hence more systematic exploration is easier particularly in case of large bacteria populations. We show that the second moment approximation predicts accurately the quantities of bacteria and polymer. Moreover, it gives relevant information about their spatial distribution.
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