固体和多孔镍钛诺植入物联合应用于外科治疗癌症患者大面积切除后胸部缺损

E. Topolnitskiy, T. Chekalkin, E. Marchenko, Y. Yasenchuk, J. Kang, L. Yahia
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引用次数: 1

摘要

胸壁肿瘤的根治性手术干预通常伴随着骨软骨结构的损害和术后复杂缺损的出现,从而导致功能和美学的损害。在广泛切除胸壁后,同时修复胸壁至关重要,包括恢复骨软骨框架和肠膜组织的完整性,以及保持纵隔和胸膜腔的解剖和生理体积。多孔和固体镍钛诺植入物及其在外科治疗中的成功应用鼓励了对癌症患者的即时和延迟骨成形术的见解。这项工作的新颖之处在于这种手术方法是使用专有方法和定制的基于niti的植入物进行切除后缺陷修复。结果表明,建议的手术方法和策略,采用一步修复是有前途的技术之一,即使这种情况加重了广泛的胸壁病变。该方法操作安全,成功率高,可作为常规手术推荐使用。联合镍钛诺植入物似乎是非常好的增强生物材料,能够可靠地修复各种大小的胸部切除术后缺陷,具有良好的功能、临床和美容效果。
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Combination of Solid and Porous Nitinol Implants in Surgical Treatment of Extensive Post-Excision Thoracic Defects in Cancer Patients
Radical surgical intervention for chest wall tumors is typically accompanied by the lesion of osteochondral structures and the appearance of complex post-resection defects, which result in functional and aesthetic impairment. After extensive resection of the chest wall, it is vitally important that it be simultaneously repaired, including restoring the osteochondral framework and the integrity of the integumentary tissues as well as maintaining the anatomical and physiological volume of the mediastinum and the pleural cavities. Porous and solid Nitinol implants and their successful deployment in surgical treatments have encouraged insights for immediate and delayed osteoplasty in cancer patients. The novel aspect of this work consists in this surgical method of post-excision defect repair is performed using a proprietary approach and customized NiTi-based implants. The results indicate that the suggested surgical approach and tactics using one-step repair are one of the promising techniques even though the case is aggravated with extensive chest wall lesions. The approach can be performed safely and can be recommended as a routine procedure with a high success rate. Combined Nitinol implants seem to be very good reinforcing biomaterials that enabled the reliable repair of thoracic post-excisional defects of various sizes with good functional, clinical, and cosmetic outcomes.
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