急性甲醇中毒并发颅内出血1例影像学表现

Adil Aytac, Erdoğan Bülbül, Bahadır Caglar
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摘要

目的:甲醇中毒是罕见的,它可以是致命的。本病例报告旨在描述急性甲醇中毒合并颅内出血的年轻患者的影像学表现。病例报告:一名32岁男性以恶心、呕吐、复视和意识不清等主诉到急诊科就诊。初次转诊时Glascow昏迷评分(GCS)为7。实验室检查显示高阴离子间隙代谢性酸中毒。通过患者的记忆诊断急性甲醇中毒。弥散加权MRI (DW-MRI)显示双脑半球壳核和扣带回类似的弥散限制病变。患者在急诊科随访时心脏骤停。经干预,他转为窦性心律,插管,并被送往重症监护病房。在第4天的随访中,GCS降至3。在脑CT上观察到左基底节区大脑出血。手术后患者仍处于昏迷状态,于入院第8天死亡。结论:急诊就诊意识改变、视力障碍及阴离子间隙高的患者应将甲醇中毒的可能性纳入鉴别诊断。DW-MRI通过检测基底神经节的对称扩散限制可能有助于诊断。此外,CT等放射学方法可用于确定病例随访期间可能发生的并发症,如出血。
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Radiology Findings in a Case of Acute Methanol Intoxication Complicated with Intracranial Hemorrhage
Aim: Methanol intoxication is rare and it can be fatal. This case report aimed to describe the radiological findings in acute methanol intoxication complicated with intracranial hemorrhage in a young patient. Case Report: A 32 year-old man applied to emergency department with a major complaints of nausea, vomiting, double vision, and confusion. Glascow coma score (GCS) was 7 at the initial referral. Laboratory tests showed high anion gap metabolic acidosis. Acute methanol intoxication was diagnosed by aid of the patient anamnesis. Diffusion-weighted MRI (DW-MRI) showed similar diffusion restriction lesions in the putamen and cingulate gyrus of both cerebral hemispheres. The patient had a cardiac arrest during follow-up in the emergency department. He was converted to sinus rhythm with the interventions, intubated, and taken to the intensive care unit. GCS reduced to 3 during follow- up at the 4th day. Cerebral intraparanchimal hemorrhage at the level of left basal ganglia was observed in the brain computed tomography (CT). He was operated however remained comatose after the operation and died at the 8th day of admission. Conclusion: Possibility of methanol intoxication should be included in the differential diagnosis in patients with altered consciousness, vision disturbances and a high anion gap admitted to the emergency service. DW-MRI may be helpful in diagnosis by detecting symmetrical diffusion restrictions at the basal ganglia. Additionally radiologic methods like CT can be used to determine complications such as bleeding that may occur during the follow-up of the cases.
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