癌症流行病学和公共卫生

Zuo‐Feng Zhang, P. Boffetta, A. Neugut, C. L. Vecchia
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引用次数: 1

摘要

肿瘤作为人类疾病和死亡的主要来源之一,继续在全球占主导地位。癌症有多种可改变的原因,了解每种癌症的归因风险因素是很重要的。本章涵盖了细胞和分子机制的作用,以及实验和流行病学方法作为主要癌症的决定因素。即使在不久的将来在癌症患者的临床管理方面取得重大发现,这些变化也将主要影响世界上富裕的部分人口。重点强调了侧重于预防已知原因并减少其后果的有希望的方法,特别是在资源有限的情况下。
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Cancer epidemiology and public health
Neoplasms continue to dominate globally as one of the major sources of human disease and death. There are multiple modifiable causes of cancer and understanding their attributable risk factors for each cancer is of importance. This chapter covers the role of cellular and molecular mechanisms as well as the experimental and epidemiological approaches as determinants of the main cancers. Even if major discoveries in the clinical management of cancer patients will be accomplished in the near future, the changes will mainly affect the affluent part of the world population. Promising approaches focused on prevention of the known causes, reducing its consequences, notably in resource-constrained settings are highlighted.
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