Anjas Wilapangga, Deni Rahmat, Rachmaniar Rachmaniar
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摘要

黄姜黄(Curcuma xanthorrhiza)被认为是一种有许多健康益处的植物,包括抗菌、抗炎、抗糖尿病和抗癌。本研究的目的是研制一种凝胶制剂,其中含有temulawak提取物纳米颗粒作为防晒霜。形成的凝胶必须进行物理评估,包括:感官,均质,粘度和涂抹性,以及pH测试和SPF检查。天竺葵提取物、纳米姜黄素的制备方法采用离子凝胶法,用粒度分析仪进行表征。结果表明,铁木犀草提取物凝胶和铁木犀草提取物纳米颗粒凝胶没有发生颜色变化,并保持均匀状态。temulawak提取物凝胶粘度为25098 cPs, temulawak提取物纳米颗粒凝胶粘度为25673 cPs。天竺葵提取物凝胶的扩散能力为6.3 cm,天竺葵提取物纳米颗粒凝胶配方的扩散能力为6.5 cm。temulawak提取物凝胶的pH值为5.61,temulawak提取物纳米颗粒凝胶的pH值为5.47。temulawak提取物凝胶的SPF值为16.77,temulawak纳米颗粒凝胶的SPF值为19.88。因此,天竺葵提取物纳米颗粒凝胶具有作为防晒凝胶的潜力。
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Formulasi dan Evaluasi Sediaan Gel Nanopartikel Ekstrak Temulawak (Curcuma xanthorrhiza) sebagai Tabir Surya
Temulawak (Curcuma xanthorrhiza) is known as a plant that has many health benefits, including antibacterial, anti-inflammatory, antidiabetic and anticancer. The purpose of this study was to formulate a gel preparation containing temulawak extract nanoparticles as a sunscreen. The gel formed must be evaluated physically including: organoleptic, homogentias, viscosity and spreadability, as well as pH test and SPF examination. Temulawak extract, Nanocurcumin manufacturing method using ionic gelation characterized using particle size analyzer. Results showed that temulawak extract gel and temulawak extract nanoparticle gel did not change color and remained in a homogeneous state. The viscosity of temulawak extract gel is 25098 cPs, while temulawak extract nanoparticle gel is 25673 cPs. The spreading ability of temulawak extract gel was 6.3 cm while the temulawak extract nanoparticle gel formula was 6.5 cm. The pH value of the temulawak extract gel was 5.61 while the pH value of the temulawak extract nanoparticle gel was 5.47. The SPF value of temulawak extract gel was 16.77 while that of temulawak nanoparticle gel was 19.88. Thus, temulawak extract nanoparticle gel can have potential as a sunscreen gel.
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