单一纤维结构不良1例的超微结构研究。

Annales d'anatomie pathologique Pub Date : 1978-01-01
G Bertrand, M F Minard, C Simard, A Rebel
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引用次数: 0

摘要

一例纤维性发育不良病例的超微结构研究结合文献中罕见的资料证实,该病变的形态特征包括典型的“编织骨”外观,不规则矿化,含有骨细胞并以成骨细胞为边界,与成纤维细胞明显不同。细胞成分总是被赋予一个大的微纹细胞质刷,显然是由硬化蛋白组成的,并表现出与低代谢活性相关的超微结构特征。肌成纤维细胞不太可能存在。光镜下可见的大量乳母细胞在电镜下显示大量的“玫瑰花”肉芽,这与骨模型中所见的乳母细胞不同。这些形态学数据并没有提供决定性的论据来支持这种病变的真正发育不良的性质。
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[Ultrastructural study of a case of monostotic fibrous dysplasia].

Ultrastructural study of a case of fibrous dysplasia taken together with the rare data in the literature confirmed that the morphological characteristics of this lesion consist of a typical appearance of "woven bone", irregularly mineralised, containing osteocytes and bordered by osteoblasts, clearly distinct from fibroblasts. The cell elements are invariably endowed with a large microbrillary cytoplasmic brush, apparently made up of scleroproteins and showing the usual ultrastructural characteristics associated with low metabolic activity. The presence of myofibroblasts is unlikely. The numerous mastocytes seen by light microscopy show a large number of "rosette" granulation at electrom microscopy, which distinguishes them from the mastocytes seen in osseous modelling. These morphological data provide no decisive argument in favour of the truly dysplasic nature of this lesion.

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