基于融合Pipit的深度卷积神经网络分类器的蛋白质结构预测模型

Swati V. Jadhav, A. J. Vyavahare
{"title":"基于融合Pipit的深度卷积神经网络分类器的蛋白质结构预测模型","authors":"Swati V. Jadhav, A. J. Vyavahare","doi":"10.1109/ESCI56872.2023.10099768","DOIUrl":null,"url":null,"abstract":"One of the main objectives of computational biology is protein structure prediction. This is important for the development of novel enzymes in biotechnology and medicine. Each protein has a certain shape and structure and our life is supported by the complex and coordinated interaction of proteins. Hence identifying the protein structure possesses various challenges and various researches are performed relying upon various classifiers. In this research a fused pipit adapted deep convolutional neural network classifier (CNN) is used for the detection of the PSS with higher accuracy. The feature extraction is made using the fused Natural language processing (NLP) based pretrained models that efficiently extracted the features and is developed using the pretrained models T5XLuniref and XLnet model. The pretrained and the deep CNN classifier is optimized effectively using the pipit optimization that mimics the foraging and the safeguarding behavior of the pipits. The enabled optimization aids in the tuning of the fusion parameters and the hyper parameters of the classifier. By measuring the improvement, the model's dominance is demonstrated, and suggested method attained an progress of 1.77 %for accuracy, 1.01 % for sensitivity and 6.90 % for specificity, which proves the efficacy of the model.","PeriodicalId":441215,"journal":{"name":"2023 International Conference on Emerging Smart Computing and Informatics (ESCI)","volume":"20 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Novel Protein Structure Prediction Model Using Fused Pipit Adapted Deep Convolutional Neural Network Classifier\",\"authors\":\"Swati V. Jadhav, A. J. Vyavahare\",\"doi\":\"10.1109/ESCI56872.2023.10099768\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"One of the main objectives of computational biology is protein structure prediction. This is important for the development of novel enzymes in biotechnology and medicine. Each protein has a certain shape and structure and our life is supported by the complex and coordinated interaction of proteins. Hence identifying the protein structure possesses various challenges and various researches are performed relying upon various classifiers. In this research a fused pipit adapted deep convolutional neural network classifier (CNN) is used for the detection of the PSS with higher accuracy. The feature extraction is made using the fused Natural language processing (NLP) based pretrained models that efficiently extracted the features and is developed using the pretrained models T5XLuniref and XLnet model. The pretrained and the deep CNN classifier is optimized effectively using the pipit optimization that mimics the foraging and the safeguarding behavior of the pipits. The enabled optimization aids in the tuning of the fusion parameters and the hyper parameters of the classifier. By measuring the improvement, the model's dominance is demonstrated, and suggested method attained an progress of 1.77 %for accuracy, 1.01 % for sensitivity and 6.90 % for specificity, which proves the efficacy of the model.\",\"PeriodicalId\":441215,\"journal\":{\"name\":\"2023 International Conference on Emerging Smart Computing and Informatics (ESCI)\",\"volume\":\"20 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2023 International Conference on Emerging Smart Computing and Informatics (ESCI)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ESCI56872.2023.10099768\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2023 International Conference on Emerging Smart Computing and Informatics (ESCI)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ESCI56872.2023.10099768","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

计算生物学的主要目标之一是蛋白质结构预测。这对生物技术和医学领域新型酶的开发具有重要意义。每种蛋白质都有一定的形状和结构,我们的生命是由蛋白质之间复杂而协调的相互作用支撑的。因此,蛋白质结构的识别面临着各种挑战,依赖于各种分类器进行各种研究。在本研究中,采用融合pipit适应深度卷积神经网络分类器(CNN)对PSS进行检测,具有较高的准确率。特征提取采用基于自然语言处理(NLP)的融合预训练模型进行,该模型能够有效地提取特征,并采用T5XLuniref和XLnet模型进行预训练。利用模拟pipit觅食和保护行为的pipit优化,对预训练和深度CNN分类器进行了有效的优化。启用的优化有助于调整融合参数和分类器的超参数。结果表明,该方法的准确率提高了1.77%,灵敏度提高了1.01%,特异性提高了6.90%,证明了该模型的有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Novel Protein Structure Prediction Model Using Fused Pipit Adapted Deep Convolutional Neural Network Classifier
One of the main objectives of computational biology is protein structure prediction. This is important for the development of novel enzymes in biotechnology and medicine. Each protein has a certain shape and structure and our life is supported by the complex and coordinated interaction of proteins. Hence identifying the protein structure possesses various challenges and various researches are performed relying upon various classifiers. In this research a fused pipit adapted deep convolutional neural network classifier (CNN) is used for the detection of the PSS with higher accuracy. The feature extraction is made using the fused Natural language processing (NLP) based pretrained models that efficiently extracted the features and is developed using the pretrained models T5XLuniref and XLnet model. The pretrained and the deep CNN classifier is optimized effectively using the pipit optimization that mimics the foraging and the safeguarding behavior of the pipits. The enabled optimization aids in the tuning of the fusion parameters and the hyper parameters of the classifier. By measuring the improvement, the model's dominance is demonstrated, and suggested method attained an progress of 1.77 %for accuracy, 1.01 % for sensitivity and 6.90 % for specificity, which proves the efficacy of the model.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
A Novel Approach to Maze Solving Algorithm Android Based Smart Appointment System (SAS) for Booking and Interacting with Teacher for Counselling A Compact Asymmetric Coplanar Strip (ACS) Antenna for WLAN and Wi-Fi Applications Insight on Human Activity Recognition Using the Deep Learning Approach Patients' Health Analysis using Machine Learning
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1